Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Aliment Pharmacol Ther. 2010 May;31(10):1141-51. doi: 10.1111/j.1365-2036.2010.04270.x. Epub 2010 Feb 18.
The role of ethnicity in the development of dyspepsia remains uncertain.
To examine the epidemiology of dyspepsia in a multi-ethnic Asian population and its impact on health-related quality of life (HRQOL).
A cross-sectional survey was conducted in a representative urban population in Kuala Lumpur, Malaysia.
A total of 2039 adults (mean +/- s.d. age: 40.5 +/- 11.8 years, males 44.2%, ethnicity: Malays 45.3%, Chinese 38.0% and Indians 13.1%, tertiary education level 62%, professional employment 47.7% and median monthly income USD 850.00) were interviewed. Dyspepsia was prevalent in 496 (24.3%) adults. Independent predictors for dyspepsia, explored by logistic regression, were identified as: Malay (OR 2.17, 95% CI = 1.57-2.99) and Indian (OR 1.59, 95% CI = 1.03-2.45) ethnicity, heavy chilli intake (OR 2.35, 95% CI = 1.15-4.80), use of regular analgesia (OR 3.51, 95% CI = 2.54-4.87) and chronic illness (OR 1.67, 95% CI = 1.22-2.28). HRQOL was assessed with the EQ-5D and significantly lower scores were noted in dyspeptics compared with healthy controls (0.85 +/- 0.17 vs. 0.95 +/- 0.12, P < 0.0001).
Ethnicity, in addition to recognized epidemiological factors, is a risk factor for dyspepsia in an urban multi-racial Asian population.
种族在消化不良发展中的作用尚不确定。
在一个多民族的亚洲人群中研究消化不良的流行病学及其对健康相关生活质量（HRQOL）的影响。
在马来西亚吉隆坡的一个代表性城市人群中进行了横断面调查。
共对 2039 名成年人（平均年龄 +/- 标准差为 40.5 +/- 11.8 岁，男性 44.2%，种族：马来人 45.3%，中国人 38.0%，印度人 13.1%，受过高等教育的 62%，专业就业的 47.7%，月收入中位数为 850.00 美元）进行了访谈。消化不良在 496 名（24.3%）成年人中很常见。通过逻辑回归确定的消化不良的独立预测因素包括：马来人（OR 2.17，95%CI = 1.57-2.99）和印度人（OR 1.59，95%CI = 1.03-2.45）种族、大量食用辣椒（OR 2.35，95%CI = 1.15-4.80）、经常使用止痛药（OR 3.51，95%CI = 2.54-4.87）和慢性疾病（OR 1.67，95%CI = 1.22-2.28）。使用 EQ-5D 评估 HRQOL，与健康对照组相比，消化不良患者的评分明显较低（0.85 +/- 0.17 vs. 0.95 +/- 0.12，P < 0.0001）。
在一个城市多民族亚洲人群中，种族除了公认的流行病学因素外，也是消化不良的一个危险因素。
