Imai H, Maotani-Imai K, Shin Y S, Ikuta K, Suehiro S, Kurimura T, Kato S, Hirai K
Section of Serology, Hokkaido University, Sapporo, Japan.
Virus Genes. 1991 Jan;5(1):81-8. doi: 10.1007/BF00571734.
A cell line (H2-5) producing defective doughnut-shaped particles of human immunodeficiency virus type I (HIV-1) was found to contain proviral DNA with a large deletion of 2558 bases, corresponding to the 3' half of pol gene, the vif and vpr genes, and the 5' terminal of the tat gene.
发现一种产生I型人类免疫缺陷病毒(HIV-1)有缺陷的环形颗粒的细胞系(H2-5),其含有前病毒DNA,该前病毒DNA有一个2558个碱基的大缺失,对应于pol基因的3'端一半、vif和vpr基因以及tat基因的5'端。