Sani Mahmoud U, Wahab Kolawole W, Yusuf Bashir O, Gbadamosi Maruf, Johnson Omolara V, Gbadamosi Akeem
Department of Medicine, Bayero University, PMB 3011, Kano, Nigeria.
BMC Res Notes. 2010 Jan 20;3:11. doi: 10.1186/1756-0500-3-11.
Cardiovascular disease (CVD) remains a major cause of morbidity and a leading contributor to mortality worldwide. Over the next 2 decades, it is projected that there will be a rise in CVD mortality rates in the developing countries, linked to demographic changes and progressive urbanization. Nigeria has witnessed tremendous socio-economic changes and rural-urban migration which have led to the emergence of non-communicable diseases. We set out to determine the prevalence of modifiable CVD risk factors among apparently healthy adult Nigerians. This is a descriptive cross-sectional study carried out at Katsina, northwestern Nigeria from March to May 2006. Subjects for the study were recruited consecutively from local residents, hospital staff and relations of in-patients of the Federal Medical Centre, Katsina using convenience sampling. Socio-demographic information, anthropometric measurements and blood pressure were obtained from the subjects in a standardized manner. Venous samples were collected for necessary investigations and analyzed at the hospital central laboratory.
Three hundred subjects (129 males and 171 females) with a mean age of 37.6 +/- 10.6 (range 18-75) years were studied. Prevalence of the modifiable cardiovascular risk factors screened for were as follows: generalized obesity 21.3% (males 10.9%, females 29.2%, p < 0.05), truncal obesity 43.7% (males 12.4%, females 67.3%, p < 0.05), hypertension 25.7% (males 27.9, females 24%, p > 0.05), type 2 diabetes mellitus 5.3% (males 5.4%, females 5.3%, p > 0.05), hypercholesterolaemia 28.3% (males 23.3%, females 32.2%, p < 0.05), elevated LDL-cholesterol 25.7% (males 28%, females 24%, p > 0.05), low HDL-cholesterol 59.3% (males 51.9%, females 65%, p < 0.05), hypertriglyceridaemia 15% (males 16.3%, females 14%, p > 0.05) and metabolic syndrome 22% (males 10.9%, females 30.4%, p < 0.05).
We found high prevalence of CVD risk factors among apparently healthy adult Nigerians. In order to reduce this high prevalence and prevent subsequent cardiovascular events, encouragement of a healthy lifestyle is suggested.
心血管疾病（CVD）仍是全球发病的主要原因及导致死亡的首要因素。预计在未来20年，发展中国家的心血管疾病死亡率将会上升，这与人口结构变化和城市化进程有关。尼日利亚经历了巨大的社会经济变革以及城乡人口迁移，这导致了非传染性疾病的出现。我们旨在确定表面健康的成年尼日利亚人中心血管疾病可改变风险因素的患病率。这是一项描述性横断面研究，于2006年3月至5月在尼日利亚西北部的卡齐纳进行。该研究的受试者通过便利抽样法从当地居民、医院工作人员以及卡齐纳联邦医疗中心住院患者的亲属中连续招募。以标准化方式从受试者处获取社会人口学信息、人体测量数据和血压。采集静脉血样进行必要检查，并在医院中心实验室进行分析。
共研究了300名受试者（129名男性和171名女性），平均年龄为37.6±10.6岁（范围18 - 75岁）。所筛查的可改变心血管风险因素的患病率如下：全身性肥胖21.3%（男性10.9%，女性29.2%，p<0.05），腹型肥胖43.7%（男性12.4%，女性67.3%，p<0.05），高血压25.7%（男性27.9%，女性24%，p>0.05），2型糖尿病5.3%（男性5.4%，女性5.3%，p>0.05），高胆固醇血症28.3%（男性23.3%，女性32.2%，p<0.05），低密度脂蛋白胆固醇升高25.7%（男性28%，女性24%，p>0.05），高密度脂蛋白胆固醇降低59.3%（男性51.9%，女性65%，p<
