Department of Internal Medicine, Sanggye-Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Korean Circ J. 2010 Feb;40(2):94-8. doi: 10.4070/kcj.2010.40.2.94. Epub 2010 Feb 23.
Primary cardiac lymphomas (PCL) are extremely rare. Clinical manifestations may be variable and are attributed to location. Here, we report on a case of PCL presenting with atrioventricular (AV) block. A 55 year-old male had experienced chest discomfort with unexplained dyspnea and night sweating. His initial electrocardiogram (ECG) revealed a first degree AV block. Along with worsening chest discomfort and dyspnea, his ECG changed to show second degree AV block (Mobitz type I). Computed tomography (CT) scan showed a cardiac mass (about 7 cm) and biopsy was performed. Pathologic finding confirmed diffuse large B-cell lymphoma. The patient was treated with multi-drug combination chemotherapy (R-CHOP: Rituximab, cyclophoshamide, anthracycline, vincristine, and prednisone). After treatment, ECG changed to show normal sinus rhythm with complete remission on follow-up CT scan.
原发性心脏淋巴瘤（PCL）极为罕见。临床表现可能多种多样，这归因于肿瘤位置。在此，我们报告一例以房室（AV）传导阻滞为表现的原发性心脏淋巴瘤。一名 55 岁男性出现原因不明的胸闷伴呼吸困难和夜间出汗。他最初的心电图（ECG）显示一度房室传导阻滞。随着胸闷和呼吸困难的加重，他的心电图改变为二度 AV 传导阻滞（Mobitz Ⅰ型）。计算机断层扫描（CT）显示心脏肿块（约 7 厘米）并进行了活检。病理检查证实弥漫性大 B 细胞淋巴瘤。患者接受了多药物联合化疗（R-CHOP：利妥昔单抗、环磷酰胺、蒽环类药物、长春新碱和泼尼松）。治疗后，心电图恢复为窦性节律，随访 CT 扫描显示完全缓解。
