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钙摄入与法国女性骨质疏松症和骨折风险的关系。

Calcium intake and the risk of osteoporosis and fractures in French women.

机构信息

Inserm ERI 12, service de rhumatologie, Amiens University Hospital, CHU Nord, place Victor-Pauchet, 80054 Amiens cedex 01, France.

出版信息

Joint Bone Spine. 2010 Mar;77(2):154-8. doi: 10.1016/j.jbspin.2009.08.007. Epub 2010 Feb 24.

Abstract

OBJECTIVES

To evaluate dietary calcium intake in postmenopausal women over 45 years of age and compare intake according to osteoporosis diagnosis and fracture history.

METHODS

A cross-sectional epidemiological survey of osteoporosis in postmenopausal women over 45 years in the general population was conducted using a stratified random sampling method and face-to-face interviews. Information was collected on osteoporosis diagnosis, fracture history and risk factors. Information on dietary calcium intake was collected using a validated questionnaire.

RESULTS

Two thousand six hundred and thirty-one women (mean age: 67.9+/-10.0 years) were included. Two hundred and fifty-four (9.7%) had received a diagnosis of osteoporosis by bone densitometry, of whom 154 (45.3%) reported at least one previous fracture. Total mean daily dietary calcium intake was 754 mg/day, of which dairy products (milk, cheese and others) were the principal source. Overall, 37.2% of the sample consumed<600 mg/day and 20.1% >1000 mg/d. The proportion of women consuming <600 mg/day increased with age (p=0.0028). No difference in mean daily calcium intake was observed between women with or without a diagnosis of osteoporosis or with or without fractures.

CONCLUSIONS

Mean dietary calcium intake in this population is well below that recommended in current national guidelines (> or =1500 mg/day), notably in those most at risk for fractures, such as women with a diagnosis of osteoporosis or those in older age groups. Intake does not appear to be influenced by osteoporosis diagnosis or fracture experience.

摘要

目的

评估 45 岁以上绝经后妇女的膳食钙摄入量,并比较根据骨质疏松症诊断和骨折史的摄入量。

方法

采用分层随机抽样方法和面对面访谈,对 45 岁以上一般人群绝经后妇女骨质疏松症进行横断面流行病学调查。收集骨质疏松症诊断、骨折史和危险因素信息。采用经过验证的问卷收集膳食钙摄入量信息。

结果

共纳入 2631 名女性(平均年龄:67.9±10.0 岁)。254 名(9.7%)通过骨密度仪诊断为骨质疏松症,其中 154 名(45.3%)报告至少有一次既往骨折。总平均每日膳食钙摄入量为 754mg/天,其中乳制品(牛奶、奶酪等)是主要来源。总体而言,37.2%的样本摄入<600mg/天,20.1%的样本摄入>1000mg/d。摄入<600mg/天的女性比例随年龄增加而增加(p=0.0028)。有无骨质疏松症诊断或骨折史的女性之间,以及有无骨折史的女性之间,平均每日钙摄入量无差异。

结论

该人群的平均膳食钙摄入量明显低于当前国家指南推荐的摄入量(>或=1500mg/天),尤其是在骨折风险最高的人群中,如骨质疏松症诊断或年龄较大的女性。摄入量似乎不受骨质疏松症诊断或骨折经历的影响。

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