Freeman Hugh J, Maguire John
University of British Columbia, Vancouver, Canada.
Can J Gastroenterol. 2010 Jan;24(1):58-60. doi: 10.1155/2010/650692.
Inflammatory bowel disease may be associated with different intracranial disorders. An inflammatory sellar mass is very rare but includes a variety of noninfectious causes including lymphocytic hypophysitis, granulomatous inflammation and Wegener's granulomatosis. A 32-year-old man was diagnosed with an inflammatory sellar mass associated with an extensive colonic inflammatory process clinically characteristic of Crohn's disease. The concurrent onset of these inflammatory disorders in distinctly separate sites may reflect their common embryological origin or represent an unusual form of metastatic Crohn's disease. Further studies are needed to determine if less overt or focal sellar inflammatory processes occur in inflammatory bowel disease, particularly in Crohn's disease because their occurrence may be critically relevant for long-term management.
炎症性肠病可能与不同的颅内疾病相关。炎性鞍区肿物非常罕见，但其包括多种非感染性病因，如淋巴细胞性垂体炎、肉芽肿性炎症和韦格纳肉芽肿。一名32岁男性被诊断为炎性鞍区肿物，同时伴有广泛的结肠炎症过程，临床特征符合克罗恩病。这些炎性疾病在截然不同的部位同时出现，可能反映了它们共同的胚胎学起源，或者代表了克罗恩病转移的一种不寻常形式。需要进一步研究以确定在炎症性肠病，尤其是克罗恩病中是否存在不太明显或局灶性的鞍区炎症过程，因为它们的发生可能与长期管理密切相关。
