Psychiatric University Outpatient Department, Psychiatric University Clinics Basel, c/o University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland.
Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1342-4. doi: 10.1016/j.pnpbp.2010.02.019. Epub 2010 Feb 24.
Hyperprolactinaemia is often found in patients with schizophrenia and usually considered a consequence of antipsychotics. Prolactin levels were measured in 43 At-Risk Mental State individuals (ARMS) and 26 patients with First Episode Psychosis (FEP). Hyperprolactinaemia was found in 25.6% of ARMS and 46.2% of FEP. Within 60 antipsychotic-naïve ARMS and FEP, hyperprolactinaemia was found in 26.7%. Hyperprolactinaemia may be pre-existing in a subgroup of patients with schizophrenia.
高催乳素血症在精神分裂症患者中很常见，通常被认为是抗精神病药物的副作用。本研究测量了 43 名处于精神病高危状态（ARMS）和 26 名首发精神病（FEP）患者的催乳素水平。结果发现，ARMS 组和 FEP 组中分别有 25.6%和 46.2%的患者催乳素水平升高。在 60 名未使用过抗精神病药物的 ARMS 和 FEP 患者中，催乳素水平升高的比例为 26.7%。高催乳素血症可能在精神分裂症患者的亚组中预先存在。
