Filardo Giuseppe, Presti Mirco Lo, Kon Elizaveta, Marcacci Maurilio
Department of Orthopedic and Sports Trauma, Biomechanics Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy.
Orthopedics. 2010 Feb;33(2):120-3. doi: 10.3928/01477447-20100104-31.
Tendon injuries, especially those of the Achilles tendon, are major concerns in sports medicine. The clinical presentation can be acute or chronic and the pathologic findings can range from peritendonitis to full-thickness tendon rupture. Nonsurgical treatment is not always successful; in particular, significant partial ruptures seem to respond poorly to conservative measures and do not improve with time. Surgery is most often considered the favored treatment option for this kind of lesion to obtain pain relief and full functionality with long-standing effects.This article describes a case of a partial tear of the Achilles tendon in a 34-year-old competitive athlete where surgical treatment was avoided in favor of a new biological approach. We applied autologous platelet growth factors through multiple platelet-rich plasma injections; approximately 6.5 billion platelets were injected into the lesion 3 times, 7 days apart. The treatment with platelet-rich plasma and a progressive rehabilitation program allowed the patient to play for 20 minutes in a basketball game 64 days after the trauma and in a full game 75 days after the trauma. To date, 18 months later, he has participated regularly in all the season's games and received no further treatment for his tendon.The fast tissue repair, confirmed by magnetic resonance and ultrasound imaging, allowed a swift return to full functionality and competitive sports activity, suggesting a possible role of platelet growth factors in promoting rapid tendon healing with high-quality tissue. This biological approach may represent a less-invasive therapeutic option even in cases where severe tendon lesions are candidates for surgical treatment.
肌腱损伤,尤其是跟腱损伤,是运动医学中的主要关注点。临床表现可为急性或慢性,病理表现范围从肌腱周围炎到全层肌腱断裂。非手术治疗并不总是成功的;特别是,严重的部分断裂对保守治疗的反应似乎很差,且不会随时间改善。手术通常被认为是治疗这类损伤的首选方法,以实现疼痛缓解和长期的完全功能恢复。本文描述了一名34岁竞技运动员跟腱部分撕裂的病例,该病例避免了手术治疗,转而采用一种新的生物治疗方法。我们通过多次注射富含血小板血浆应用自体血小板生长因子;约65亿个血小板分3次注射到损伤部位,每次间隔7天。富含血小板血浆治疗和逐步的康复计划使患者在受伤64天后能在篮球比赛中上场20分钟,在受伤75天后能参加全场比赛。到目前为止,18个月后,他已定期参加了整个赛季的比赛,且其肌腱未再接受进一步治疗。磁共振和超声成像证实的快速组织修复,使患者能迅速恢复完全功能和竞技体育活动,这表明血小板生长因子在促进肌腱快速愈合及形成高质量组织方面可能发挥作用。这种生物治疗方法可能代表了一种侵入性较小的治疗选择,即使在严重肌腱损伤适合手术治疗的情况下也是如此。