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重症监护病房的姑息治疗团队:一项随机对照可行性研究。

Palliative care teams in the intensive care unit: a randomised, controlled, feasibility study.

机构信息

Department of Intensive Care, Concord Repatriation General Hospital, Sydney, NSW.

出版信息

Crit Care Resusc. 2010 Mar;12(1):28-35.

Abstract

OBJECTIVES

To determine whether palliative care teams can improve patient, family and staff satisfaction for patients receiving end-of-life care in the intensive care unit and reduce surrogate markers of health care costs.

DESIGN

Randomised controlled, feasibility study.

SETTING

14-bed general ICU over 29 months in 2006-2008.

PARTICIPANTS

Patients admitted with a terminal or preterminal condition, for whom the treating intensivist considered that escalating or continuing treatment was unlikely to achieve significant improvement in the patient's clinical condition.

INTERVENTION

A consultation from a palliative care team, in addition to usual ICU end-of-life care.

MAIN OUTCOME MEASURES

ICU and hospital length of stay, and changes in composite scores of satisfaction obtained from questionnaires administered to families, nursing staff and intensivists.

RESULTS

The study was constrained by significant logistical and methodological problems, including low recruitment and questionnaire completion rates, and the lack of an available validated questionnaire. From a total of 2009 admissions over a 29-month period, 20 patients were enrolled, 10 in each group. There were significant differences in baseline characteristics. There were no statistically significant differences between those who had a consultation with the palliative care team and those who did not in median ICU length of stay (3 days v 5 days, P=0.97), median hospital length of stay (5 days v 11 days, P=0.44), or changes in overall composite satisfaction scores reported by families (-6% v -6%, P=0.91), nursing staff (+5% v +15%, P=0.30), and intensivists (-2% v +2%, P=0.42).

CONCLUSION

This feasibility study was difficult to conduct and did not generate any robust conclusions about the utility of involving palliative care teams in end-of-life care in the ICU. Larger studies are technically possible but unlikely to be feasible.

TRIAL REGISTRATION

Australian Clinical Trials Registry ACTRN012606000110583.

摘要

目的

确定姑息治疗团队是否可以提高接受重症监护病房临终关怀患者的患者、家属和工作人员的满意度,并降低卫生保健成本的替代标志物。

设计

随机对照、可行性研究。

设置

2006 年至 2008 年间,在一个 14 张床位的普通 ICU 中进行,为期 29 个月。

参与者

入住时患有终末期或终末期疾病的患者,其主治重症医师认为,升级或继续治疗不太可能显著改善患者的临床状况。

干预措施

姑息治疗团队的咨询,除了常规的 ICU 临终关怀。

主要观察指标

ICU 和医院的住院时间,以及通过向家属、护理人员和重症医师发放问卷获得的综合满意度评分的变化。

结果

该研究受到严重的后勤和方法学问题的限制,包括低招募率和问卷完成率,以及缺乏可用的经过验证的问卷。在 29 个月的时间里,共有 2009 名患者入院,每组 10 名患者入组。两组患者的基线特征存在显著差异。接受姑息治疗团队咨询的患者与未接受咨询的患者在 ICU 中位住院时间(3 天对 5 天,P=0.97)、中位医院住院时间(5 天对 11 天,P=0.44)或家庭(-6%对-6%,P=0.91)、护理人员(+5%对+15%,P=0.30)和重症医师(-2%对+2%,P=0.42)的整体综合满意度评分变化方面无统计学显著差异。

结论

这项可行性研究难以进行,并未得出有关在 ICU 中临终关怀中涉及姑息治疗团队的实用性的任何可靠结论。更大规模的研究在技术上是可行的,但不太可能可行。

试验注册

澳大利亚临床试验注册 ACTRN012606000110583。

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