Fira-Mladinescu Corneluţa, Fira-Mladinescu O, Doroftei Sorina, Sas Felicia, Ursoniu S, Ionuţ R, Putnoky Salomeia, Suciu Oana, Vlaicu Brigitha
Centrul de Studii in Medicină Preventivă, Universitatea de Medicină si Farmacie "V. Babeş" Timişõara.
Rev Med Chir Soc Med Nat Iasi. 2008 Jul-Sep;112(3):805-11.
The aim of the present study performed in a Romanian population was to identify the food which can be either associated with or protect against colorectal carcinoma.
Correlation and regression analysis were used to examine the association between dietary intake and the rate of incidence for colon, rectum and anus cancers, in study groups from 7 regions of Romania.
A strong and positive association was observed for colonic cancer and the intake of coffee, tea and cocoa (r = 0.77, p = 0.042) whereas statistical significance of borderline value was found for margarine (r = 0.73, p = 0.06) and sweets (r = 0.74, p = 0.066) intake. A potential protective effect can be attributed to wine consumption ( r = -0.75, p = 0.03). The malignancies of the rectum and anus showed both a strong positive correlation with the intake of red meat ( r = 0.76, p = 0.048), sausages ( r = 0.87, p = 0.012), margarine (r = 0.97, p = 0.0004), butter ( r = 0.76, p = 0.049), sweets ( r = 0.93, p = 0.003), beverages (r = 0.97, p = 0.0003), coffee, tea, cocoa ( r = 0.94, p = 0.002). Negative correlations were reported for the recto-anal cancer and the consumption of: fish (r = -0.8, p = 0.032), cheese (r = -0.9, p = 0.006), wine (r = -0.85, p = 0.015).
The need for reducing the dietary intake of margarine, red meat, sausages and sweets while the beneficial effects of wine consumption have been also confirmed.
本研究在罗马尼亚人群中开展，目的是确定可能与结直肠癌相关或预防结直肠癌的食物。
采用相关性和回归分析，研究罗马尼亚7个地区的研究组中饮食摄入量与结肠癌、直肠癌和肛管癌发病率之间的关联。
观察到结肠癌与咖啡、茶和可可的摄入量呈强正相关（r = 0.77，p = 0.042），而人造黄油（r = 0.73，p = 0.06）和甜食（r = 0.74，p = 0.066）的摄入量具有临界值的统计学意义。饮用葡萄酒可能具有保护作用（r = -0.75，p = 0.03）。直肠癌和肛管癌与红肉（r = 0.76，p = 0.048）、香肠（r = 0.87，p = 0.012）、人造黄油（r = 0.97，p = 0.0004）、黄油（r = 0.76，p = 0.049）、甜食（r = 0.93，p = 0.003）、饮料（r = 0.97，p = 0.0003）、咖啡、茶、可可（r = 0.94，p = 0.002）的摄入量均呈强正相关。直肠癌和肛管癌与鱼类（r = -0.8，p = 0.032）、奶酪（r = -0.9，p = 0.006）、葡萄酒（r = -0.85，p = 0.015）的摄入量呈负相关。
需要减少人造黄油、红肉、香肠和甜食的饮食摄入量，同时饮用葡萄酒的有益作用也得到了证实。
