University of Cambridge, Cambridge, UK.
J Cogn Neurosci. 2011 Feb;23(2):404-13. doi: 10.1162/jocn.2010.21450. Epub 2010 Mar 4.
The left inferior frontal gyrus (LIFG) has long been claimed to play a key role in language function. However, there is considerable controversy as to whether regions within LIFG have specific linguistic or domain-general functions. Using fMRI, we contrasted linguistic and task-related effects by presenting simple and morphologically complex words while subjects performed a lexical decision (LD) task or passively listened (PL) without making an overt response. LIFG Brodmann's area 47 showed greater activation in LD than PL, whereas LIFG Brodmann's area 44 showed greater activation to complex compared with simple words in both tasks. These results dissociate task-driven and obligatory language processing in LIFG and suggest that PL is the paradigm of choice for probing the core aspects of the neural language system.
左额下回（LIFG）一直被认为在语言功能中起着关键作用。然而，关于 LIFG 内的区域是否具有特定的语言或非语言的一般功能，存在着相当大的争议。我们使用 fMRI 通过呈现简单和形态复杂的单词来对比语言和任务相关的影响，而被试执行词汇判断（LD）任务或被动聆听（PL）而不做出明显的反应。LIFG 的布罗德曼区 47 在 LD 中比 PL 显示出更大的激活，而 LIFG 的布罗德曼区 44 在两个任务中对复杂词比对简单词显示出更大的激活。这些结果将 LIFG 中的任务驱动和强制性语言处理分开，并表明 PL 是探测神经语言系统核心方面的首选范例。
