Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Trends Parasitol. 2010 Apr;26(4):180-9. doi: 10.1016/j.pt.2010.02.005. Epub 2010 Mar 2.
Molecular data have defined seven genetic Assemblages of Giardia duodenalis, named A-G. Humans are infected with Assemblages A and B, dogs primarily with C and D, and cats with F. Assemblage A has been subclassified into subtypes A-I to A-IV: A-I has been reported in humans and animals, A-II in humans, and A-III and IV exclusively in animals. Assemblage B has broad host specificity infecting humans and animals. Recently, small numbers of dogs and cats have been reported to also carry Assemblages A-I or B. Because these genotypes are found primarily in humans, and no comprehensive studies to address zoonotic transmission of G. duodenalis are yet available, the potential role of dogs and cats cannot be conclusively excluded.
分子数据定义了 7 种肠贾第鞭毛虫基因集合,分别命名为 A-G。人类感染 A 和 B 集合,狗主要感染 C 和 D,猫感染 F。A 集合已进一步细分为 A-I 到 A-IV 亚型:A-I 已在人和动物中报道,A-II 仅在人中报道,A-III 和 A-IV 仅在动物中报道。B 集合具有广泛的宿主特异性,感染人类和动物。最近,有少量的狗和猫也被报道携带 A-I 或 B 集合。由于这些基因型主要存在于人类中,且目前尚无全面研究来解决肠贾第鞭毛虫的人畜共患传播问题,因此不能排除狗和猫的潜在作用。