Institute for Health Services Research in Dermatology, University Clinics Hamburg-Eppendorf, Hamburg, Germany. m.radtke @ uke.de
Dermatology. 2010;220(3):194-200. doi: 10.1159/000275657. Epub 2010 Mar 5.
Vitiligo causes substantial disease burden and patient needs still remain underestimated.
To assess the clinical features, treatment outcomes and satisfaction in patients with vitiligo.
A nationwide, cross-sectional German postal survey was conducted. Clinical features and treatment outcomes of vitiligo (affected body surface, comorbidities, treatments applied, patient benefit index [PBI]) were evaluated using a standardized patient questionnaire.
1,023 patients (71.4% women, mean age 44.4 years) completed the questionnaire. The average onset of disease was at 24.1 years, and the mean disease duration was 20.3 years. The mean number of body sites affected was 6.9, and the mean affected body surface area was 14.9%. On average, 3.7 therapies had been applied previously, with a total PBI of 1.03 +/- 1.12. Only 38.7% experienced a PBI >1, which indicates a minimal patient benefit.
Most therapeutic options are considered to be of low patient benefit. There is a need for more beneficial treatments and improved care in patients with vitiligo.
白癜风会导致严重的疾病负担，患者的需求仍被低估。
评估白癜风患者的临床特征、治疗效果和满意度。
进行了一项全国性的、横断面的德国邮政调查。使用标准化患者问卷评估白癜风的临床特征和治疗效果（受累体表面积、合并症、应用的治疗方法、患者获益指数[PBI]）。
1023 名患者（71.4%为女性，平均年龄 44.4 岁）完成了问卷。疾病的平均发病年龄为 24.1 岁，平均病程为 20.3 年。平均受累体表面积为 6.9，平均受累体表面积为 14.9%。平均之前应用过 3.7 种治疗方法，总 PBI 为 1.03 +/- 1.12。只有 38.7%的患者 PBI>1，这表明患者获益极小。
大多数治疗选择被认为对患者的获益较低。白癜风患者需要更有效的治疗和更好的护理。
