Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina.
J Atten Disord. 2011 Oct;15(7):545-56. doi: 10.1177/1087054709359887. Epub 2010 Mar 5.
To investigate the presence of apathy symptoms in adolescents and adults with ADHD as a behavioral manifestation of underlying motivational deficits and to determine whether apathy symptoms were associated with a specific neuropsychological profile.
A total of 38 ADHD participants (28 of the combined subtype [ADHD/C] and 10 of the inattentive subtype [ADHD/I]) and 30 healthy controls (Ctrl) were assessed on two measures of apathy administered to subjects and informants. As well, ADHD participants completed a comprehensive neuropsychological battery.
ADHD participants presented elevated scores on measures of apathy relative to controls (ADHD/I > ADHD/C > Ctrl). Informant-based ratings of apathy correlated significantly with behavioral measures of inattention. Apathy measures correlated significantly with executive tests, working memory, verbal fluency, and general intellectual abilities, only in the inattentive sample.
This study stresses the relevance of motivational deficits in adult ADHD as a significant clinical dimension closely linked to inattention and executive difficulties.
探讨 ADHD 青少年和成人患者中是否存在淡漠症状，这些症状是否是潜在动机缺陷的行为表现，并确定淡漠症状是否与特定的神经心理学特征相关。
共评估了 38 名 ADHD 参与者（28 名混合型 [ADHD/C] 和 10 名注意力不集中型 [ADHD/I]）和 30 名健康对照者（Ctrl），他们接受了两种针对患者和知情者的淡漠症状评估。此外，ADHD 参与者还完成了全面的神经心理学测试。
与对照组相比，ADHD 参与者在淡漠症状评估上的得分更高（ADHD/I > ADHD/C > Ctrl）。基于知情者的淡漠评定与注意力不集中的行为评估显著相关。只有在注意力不集中组中，淡漠评估与执行测试、工作记忆、言语流畅性和一般智力能力显著相关。
本研究强调了动机缺陷在成人 ADHD 中的重要性，这是与注意力不集中和执行困难密切相关的重要临床维度。
