Kasová V, Brůcková M
Zentralbl Bakteriol Orig A. 1977 Sep;239(1):1-9.
An outbreak of epidemic keratoconjunctivitis (EKC) occurred in northern Bohemia in the summer of 1975. One hundred and four patients were treated. Four strains of adenovirus type 29 with low or strong pronounced cross-neutralization against anti-Ad 15 reference serum, and 2 adenovirus type 8 were isolated of 4 patients. Type 8 strains were only obtained from conjunctiva, type 29 also from stools. From one patient, type 8 from conjunctiva and type 29 from stool were isolated simultaneously. Out of 22 patients with demonstrable antibody rise, a monotypic response in virus-neutralization test against type 29 was detected in 13 and a mixed response against types 29 and 8 in nine. An antibody rise was most frequently demonstrated by virus-neutralization test, the frequence for VNT alone being equal to the frequency of antibody rise as detected by VNT, hemagglutination-inhibition test and complement-fixation test in combination.
1975年夏天，波希米亚北部爆发了流行性角结膜炎（EKC）。对104例患者进行了治疗。从4例患者中分离出4株29型腺病毒，它们对15型腺病毒参考血清有低或强的明显交叉中和作用，以及2株8型腺病毒。8型毒株仅从结膜中分离得到，29型毒株也从粪便中分离得到。从1例患者中同时分离出结膜中的8型毒株和粪便中的29型毒株。在22例抗体呈上升趋势的患者中，13例在病毒中和试验中对29型呈现单型反应，9例对29型和8型呈现混合反应。抗体上升最常通过病毒中和试验证实，单独病毒中和试验的频率与病毒中和试验、血凝抑制试验和补体结合试验联合检测到的抗体上升频率相当。
