Department of Respiratory medicine, Royal Infirmary of Edinburg, 51 Little France crescent, Edinburgh EHI64SA, UK.
QJM. 2010 Jun;103(6):379-85. doi: 10.1093/qjmed/hcq023. Epub 2010 Mar 15.
Inhaled corticosteroids (ICS) are commonly used in the treatment of chronic obstructive pulmonary disease. Recent large prospective trials have reported an increased incidence of pneumonia in patients treated with ICS. Despite this, the link between ICS and pneumonia remains controversial. In this review, pro and con arguments for the association between ICS and increased pneumonia risk are discussed, drawing on evidence from experimental and clinical research.
吸入性皮质类固醇（ICS）常用于治疗慢性阻塞性肺疾病。最近的大型前瞻性试验报告称，接受 ICS 治疗的患者肺炎发病率增加。尽管如此，ICS 和肺炎之间的联系仍存在争议。在这篇综述中，我们根据实验和临床研究的证据，讨论了 ICS 与增加肺炎风险之间关联的正反两方面观点。
