金黄色葡萄球菌临床分离株对司帕沙星和诺氟沙星的摄取情况。
Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus.
作者信息
Yoshida S, Kojima T, Inoue M, Mitsuhashi S
机构信息
Episome Institute, Gunma, Japan.
出版信息
Antimicrob Agents Chemother. 1991 Feb;35(2):368-70. doi: 10.1128/AAC.35.2.368.
Abstract
The amount of sparfloxacin uptake was higher than that of norfloxacin uptake in Staphylococcus aureus. Moreover, energy-dependent reduction in quinolone uptake, probably due to active efflux of the quinolone, was observed. The reduction in quinolone uptake appeared to be associated with quinolone resistance in S. aureus.
摘要
在金黄色葡萄球菌中，司帕沙星的摄取量高于诺氟沙星的摄取量。此外，观察到喹诺酮摄取的能量依赖性降低，这可能是由于喹诺酮的主动外排所致。喹诺酮摄取的降低似乎与金黄色葡萄球菌对喹诺酮的耐药性有关。
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