Garrett V D, Brantley P J, Jones G N, McKnight G T
Louisiana State University, Baton Rouge 70803.
J Behav Med. 1991 Feb;14(1):87-96. doi: 10.1007/BF00844770.
This study examined the effect of minor daily stressors on the primary indices of Crohn's disease in 10 adult volunteers from a support group for individuals with inflammatory bowel disease. All subjects monitored the occurrence of daily stress concurrently with the signs and symptoms of their disease for 28 days. The results of the regression and between-subject analyses indicate a relation between daily stress and self-rated disease severity in Crohn's disease. The effects of daily stress on signs and symptoms of Crohn's disease were significant even after controlling for the effects of major life events. Individual within-subject correlations, however, indicated that stress and indicators of disease were highly related for only three subjects. The results of the current study therefore suggest that at least for some individuals with Crohn's disease, daily stress is related to self-reported indicators of the illness.
本研究对10名来自炎症性肠病患者支持小组的成年志愿者进行了调查，探究日常轻微应激源对克罗恩病主要指标的影响。所有受试者在28天内同时监测日常应激的发生情况以及自身疾病的体征和症状。回归分析和受试者间分析的结果表明，日常应激与克罗恩病患者自我评定的疾病严重程度之间存在关联。即使在控制了重大生活事件的影响之后，日常应激对克罗恩病体征和症状的影响仍然显著。然而，个体受试者内的相关性表明，只有三名受试者的应激与疾病指标高度相关。因此，本研究结果表明，至少对于一些克罗恩病患者来说，日常应激与疾病的自我报告指标有关。
