Department of Prosthodontics and Research Institute of Oral Science, College of Dentistry, Kangnung-Wonju National University, Gangneung, Korea.
Clin Oral Implants Res. 2010 Aug;21(8):848-56. doi: 10.1111/j.1600-0501.2009.01862.x. Epub 2010 Apr 4.
This study examined the bone response of magnesium (Mg) ion-implanted implants produced using a plasma source ion implantation method.
The surface characteristics were evaluated by scanning electron microscopy, Auger electron spectroscopy, X-ray photoelectron spectroscopy, and Rutherford backscattering spectroscopy. The screw-type titanium implants were treated with resorbable blasting media (RBM) and divided into one control group (RBM implants) and three test groups (Mg ion-implanted implants with different retained Mg doses). Twenty-four implants from each group were placed into the tibiae of 24 New Zealand white rabbits. After allowing 6 weeks for healing, the removal torque (RTQ) was measured and the implants were subjected to histomorphometric analysis.
The surface roughness and surface morphology of the test groups were similar. The Mg ion-implanted implants with a 2.3 x 10(15) ions/cm(2) retained dose showed a significantly higher RTQ than the other implants. Histomorphometric analysis indicated that the bone contact of this group was superior to the other groups.
The bone response of Mg ion-implanted implant showed results superior or similar to an RBM-treated implant. The optimal Mg ion concentration that induced the strongest osseointegration was approximately 9%.
本研究探讨了采用等离子源离子注入法制备的镁（Mg）离子注入种植体的骨反应。
通过扫描电子显微镜、俄歇电子能谱、X 射线光电子能谱和卢瑟福背散射光谱评估表面特性。将螺旋式钛种植体用可吸收喷丸介质（RBM）处理，并分为对照组（RBM 种植体）和三组实验组（不同残留 Mg 剂量的 Mg 离子注入种植体）。每组 24 个种植体植入 24 只新西兰白兔的胫骨中。在愈合 6 周后，测量了去除扭矩（RTQ），并对种植体进行了组织形态计量学分析。
实验组的表面粗糙度和表面形貌相似。2.3 x 10(15)ions/cm(2)残留剂量的 Mg 离子注入种植体的 RTQ 明显高于其他种植体。组织形态计量学分析表明，该组的骨接触优于其他组。
Mg 离子注入种植体的骨反应结果优于或等同于 RBM 处理种植体。诱导最强骨整合的最佳 Mg 离子浓度约为 9%。
