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死亡器官捐献规则:它能经受住严格审查吗?

The dead donor rule: can it withstand critical scrutiny?

作者信息

Miller Franklin G, Truog Robert D, Brock Dan W

机构信息

National Institutes of Health, Bethesda, MD 20892-1156, USA.

出版信息

J Med Philos. 2010 Jun;35(3):299-312. doi: 10.1093/jmp/jhq019. Epub 2010 May 3.

DOI:10.1093/jmp/jhq019
PMID:20439355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3916748/
Abstract

Transplantation of vital organs has been premised ethically and legally on "the dead donor rule" (DDR)-the requirement that donors are determined to be dead before these organs are procured. Nevertheless, scholars have argued cogently that donors of vital organs, including those diagnosed as "brain dead" and those declared dead according to cardiopulmonary criteria, are not in fact dead at the time that vital organs are being procured. In this article, we challenge the normative rationale for the DDR by rejecting the underlying premise that it is necessarily wrong for physicians to cause the death of patients and the claim that abandoning this rule would exploit vulnerable patients. We contend that it is ethical to procure vital organs from living patients sustained on life support prior to treatment withdrawal, provided that there is valid consent for both withdrawing treatment and organ donation. However, the conservatism of medical ethics and practical concerns make it doubtful that the DDR will be abandoned in the near future. This leaves the current practice of organ transplantation based on the "moral fiction" that donors are dead when vital organs are procured.

摘要

重要器官移植在伦理和法律上一直以“死亡供体规则”(DDR)为前提——即要求在获取这些器官之前确定供体已经死亡。然而,学者们有力地论证了,重要器官的供体,包括那些被诊断为“脑死亡”的供体以及根据心肺标准被宣布死亡的供体,在获取重要器官时实际上并未死亡。在本文中,我们通过拒绝其潜在前提(即医生导致患者死亡必然是错误的)以及放弃该规则会剥削弱势患者的说法,来挑战DDR的规范依据。我们认为,在撤掉维持生命支持治疗之前,从依赖生命支持维持生命的活体患者身上获取重要器官是符合伦理的,前提是撤掉治疗和器官捐献都有有效的同意。然而,医学伦理的保守性和实际问题使得DDR在近期被放弃的可能性存疑。这使得当前基于“道德虚构”(即在获取重要器官时供体已死亡)的器官移植做法得以延续。

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J Heart Lung Transplant. 2024 Jun;43(6):1021-1029. doi: 10.1016/j.healun.2024.02.1455. Epub 2024 Mar 2.
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Brain Death and the Dutch Organ Donation Law.脑死亡与荷兰器官捐赠法
Linacre Q. 2020 May;87(2):161-170. doi: 10.1177/0024363919897441. Epub 2020 Jan 6.
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本文引用的文献

1
Moral fictions and medical ethics.道德虚构与医学伦理学。
Bioethics. 2010 Nov;24(9):453-60. doi: 10.1111/j.1467-8519.2009.01738.x.
2
Rethinking the ethics of vital organ donations.重新思考重要器官捐赠的伦理问题。
Hastings Cent Rep. 2008 Nov-Dec;38(6):38-46. doi: 10.1353/hcr.0.0085.
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Pediatric heart transplantation after declaration of cardiocirculatory death.心肺循环死亡宣告后的小儿心脏移植
N Engl J Med. 2008 Aug 14;359(7):709-14. doi: 10.1056/NEJMoa0800660.
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Donating hearts after cardiac death--reversing the irreversible.心脏死亡后捐献心脏——逆转不可逆转之事。
N Engl J Med. 2008 Aug 14;359(7):672-3. doi: 10.1056/NEJMp0805451.
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Extended somatic support for a pregnant woman with brain death from metastatic malignant melanoma: a case report.对一名因转移性恶性黑色素瘤导致脑死亡的孕妇的长期躯体支持:一例病例报告。
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Organ donation after cardiac death.心脏死亡后的器官捐献
N Engl J Med. 2007 Jul 19;357(3):209-13. doi: 10.1056/NEJMp078066.
7
Brain death - too flawed to endure, too ingrained to abandon.脑死亡——缺陷太多难以存续,却又根深蒂固难以摒弃。
J Law Med Ethics. 2007 Summer;35(2):273-81. doi: 10.1111/j.1748-720X.2007.00136.x.
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The prolongation of somatic support in a pregnant woman with brain-death: a case report.脑死亡孕妇的躯体支持延长:一例报告。
Reprod Health. 2006 Apr 27;3:3. doi: 10.1186/1742-4755-3-3.
9
Death and organ procurement: public beliefs and attitudes.死亡与器官获取:公众的观念与态度
Soc Sci Med. 2004 Dec;59(11):2325-34. doi: 10.1016/j.socscimed.2004.03.029.
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The internal morality of medicine: an evolutionary perspective.医学的内在道德:一种进化的视角。
J Med Philos. 2001 Dec;26(6):581-99. doi: 10.1076/jmep.26.6.581.2993.