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比较个体化饮食咨询与标准营养护理对头颈部癌症放疗患者减肥效果的影响。

Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy.

机构信息

Department of Gastroenterology and Hepatology - Dietetics (367), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

出版信息

Br J Nutr. 2010 Sep;104(6):872-7. doi: 10.1017/S0007114510001315. Epub 2010 May 5.

Abstract

Clinical research shows that nutritional intervention is necessary to prevent malnutrition in head and neck cancer patients undergoing radiotherapy. The objective of the present study was to assess the value of individually adjusted counselling by a dietitian compared to standard nutritional care (SC). A prospective study, conducted between 2005 and 2007, compared individual dietary counselling (IDC, optimal energy and protein requirement) to SC by an oncology nurse (standard nutritional counselling). Endpoints were weight loss, BMI and malnutrition (5% weight loss/month) before, during and after the treatment. Thirty-eight patients were included evenly distributed over two groups. A significant decrease in weight loss was found 2 months after the treatment (P = 0.03) for IDC compared with SC. Malnutrition in patients with IDC decreased over time, while malnutrition increased in patients with SC (P = 0.02). Therefore, early and intensive individualised dietary counselling by a dietitian produces clinically relevant effects in terms of decreasing weight loss and malnutrition compared with SC in patients with head and neck cancer undergoing radiotherapy.

摘要

临床研究表明,营养干预对于预防头颈部癌症患者在放疗过程中发生营养不良是必要的。本研究旨在评估营养师进行个体化咨询与肿瘤护士提供标准营养护理(SC)相比的价值。本前瞻性研究于 2005 年至 2007 年进行,将个体饮食咨询(IDC,最佳能量和蛋白质需求)与肿瘤护士提供的 SC(标准营养咨询)进行了比较。终点是治疗前后的体重减轻、BMI 和营养不良(每月体重减轻 5%)。38 例患者平均分配到两组。与 SC 相比,IDC 治疗后 2 个月体重减轻明显减少(P = 0.03)。IDC 患者的营养不良随时间减少,而 SC 患者的营养不良增加(P = 0.02)。因此,与 SC 相比,营养师进行早期和强化的个体化饮食咨询对头颈部癌症放疗患者在减轻体重减轻和营养不良方面具有临床相关效果。

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