Domìnguez V, Calle E, Ortega P, Astasio P, Valero de Bernabè J, Rey Calero J
Dpto de Salúd Pública, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
Eur J Epidemiol. 1991 Mar;7(2):171-4. doi: 10.1007/BF00237362.
A cross-sectional case-control study was performed to identify some obstetric and gynaecologic factors that can influence spontaneous abortion. Statistical and epidemiologic analyses were done by multiple logistic regression to adjust OR through the beta coefficient. A dicotomized outcome variable, representing spontaneous abortion, and different independent variables, representing distinct medical factors, were designed. The analysis was carried out with a personal computer and an appropriate statistic package. The variables representing age over 35 and previous spontaneous abortions were shown to be risk factors, adjusted for the rest of variables. The variables representing parity and late menarcheal age lost significance when they were adjusted with multiple logistic regression.
进行了一项横断面病例对照研究,以确定一些可能影响自然流产的妇产科因素。通过多元逻辑回归进行统计和流行病学分析,以通过β系数调整比值比(OR)。设计了一个代表自然流产的二分结局变量和代表不同医学因素的不同自变量。使用个人电脑和适当的统计软件包进行分析。在对其他变量进行调整后,代表35岁以上年龄和既往自然流产的变量被证明是危险因素。当通过多元逻辑回归进行调整时,代表产次和初潮年龄较晚的变量失去了显著性。