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加拿大绵羊非典型痒病的鉴定

Identification of atypical scrapie in Canadian sheep.

作者信息

Mitchell Gordon B, O'Rourke Katherine I, Harrington Noel P, Soutyrine Andrei, Simmons Marion M, Dudas Sandor, Zhuang Dongyue, Laude Hubert, Balachandran Aru

机构信息

Canadian Food Inspection Agency, Ottawa Laboratory-Fallowfield, 3851 Fallowfield Road, Ottawa, Ontario, Canada, K2H 8P9.

出版信息

J Vet Diagn Invest. 2010 May;22(3):408-11. doi: 10.1177/104063871002200310.

DOI:10.1177/104063871002200310
PMID:20453215
Abstract

Scrapie, a transmissible spongiform encephalopathy of sheep and goats, exists in most small ruminant-producing countries of the world. A novel form of this disease was recently recognized and is known by various names, including Nor98, Nor98-like, and atypical scrapie. Differing from classic scrapie in epidemiology, histopathology, and biochemical characteristics, atypical scrapie cases have been identified throughout Europe and in the United States. Enhanced scrapie surveillance efforts recently identified 3 cases of atypical scrapie in Canada.

摘要

羊瘙痒症是绵羊和山羊的一种传染性海绵状脑病,存在于世界上大多数小型反刍动物生产国。这种疾病的一种新形式最近被确认,有多种名称,包括Nor98、Nor98样和非典型羊瘙痒症。非典型羊瘙痒症在流行病学、组织病理学和生化特征方面与经典羊瘙痒症不同,在欧洲和美国各地都已发现相关病例。最近加强的羊瘙痒症监测工作在加拿大发现了3例非典型羊瘙痒症病例。

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1
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2
[Transmissible spongiform encephalopathies in sheep and goats].[绵羊和山羊的传染性海绵状脑病]
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PrPres in placental tissue following experimental transmission of atypical scrapie in ARR/ARR sheep is not infectious by Tg338 mouse bioassay.经实验性传播非典型羊瘙痒病后,ARR/ARR 绵羊胎盘组织中的 PrPres 用 Tg338 小鼠生物测定法检测不具有感染性。
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