Thomas C, Driessen M, Arolt V
Abteilung Gerontopsychiatrie, Klinik für Psychiatrie und Psychotherapie Bethel, Evangelisches Krankenhaus Bielefeld, Gilead III, Bethesdaweg 12, 33617, Bielefeld, Deutschland.
Nervenarzt. 2010 May;81(5):613-28; quiz 629-30. doi: 10.1007/s00115-010-3013-9.
Psychiatric disorders due to a medical or neurological condition are the main differential diagnoses in newly admitted psychiatric patients, consultations and outpatient settings. Especially with the growing elderly population delirium occurs more frequently, often due to multiple causes. Although its prognosis is known to be unfavourable, delirium too often remains undiagnosed or untreated. Medications, neurological diseases, infections as well as metabolic and other medical conditions have to be ruled out in the differential diagnosis using the patient's history, physical examination, laboratory results and imaging procedures. First-time psychiatric symptoms of an unknown medical disease as well as co-occurring psychiatric symptoms in chronic diseases provoke a challenging diagnostic decision, as reactive psychiatric symptoms have to be distinguished which is not always possible. In psychiatric disorders confirmed to be due to a medical condition, therapeutic implications are primarily geared to the causes of the disease. Only in a second step psychiatric medication is warranted with antipsychotic, antidepressant or sedation-inducing properties depending on the patient's symptoms.
由医学或神经疾病引起的精神障碍是新入院精神科患者、会诊及门诊环境中的主要鉴别诊断。尤其是随着老年人口的增加,谵妄的发生更为频繁,往往由多种原因导致。尽管已知其预后不佳,但谵妄常常仍未得到诊断或治疗。在鉴别诊断中,必须利用患者的病史、体格检查、实验室结果和影像学检查排除药物、神经疾病、感染以及代谢和其他医学状况。未知医学疾病的首次精神症状以及慢性病中共存的精神症状引发了具有挑战性的诊断决策,因为必须区分反应性精神症状,而这并不总是可行的。在确诊为由医学状况引起的精神障碍中,治疗主要针对疾病的病因。只有在第二步,才根据患者的症状使用具有抗精神病、抗抑郁或诱导镇静作用的精神科药物。