Andreou Andreas, Glanemann Matthias, Guckelberger Olaf, Denecke Timm, Grieser Christian, Podrabsky Petr, Neuhaus Peter
Klinik für Allgemein-, Visceral- und Transplantationschirurgie, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.
Med Klin (Munich). 2010 Apr;105(4):227-31. doi: 10.1007/s00063-010-1031-9.
Locally advanced cancer of the body of the pancreas with infiltration of the celiac trunk and its branches is often considered an unresectable disease. Distal pancreatectomy with resection of the celiac trunk was described as a new concept for the curative treatment of these tumors.
The case of a 61-year-old female patient is reported, who underwent distal pancreatectomy with splenectomy and resection of the celiac trunk for locally advanced cancer of the pancreatic body with infiltration of the celiac trunk. The celiac trunk was embolized preoperatively in order to assure arterial perfusion of the liver.
Distal pancreatectomy with en bloc resection of the celiac trunk offers a high resectability rate and thus a curative option for locally advanced cancer of the pancreatic body with vascular invasion. The optimization of patient selection and the development of effective adjuvant chemotherapy could significantly improve the survival of patients subjected to this operation.
伴有腹腔干及其分支浸润的局部晚期胰体癌通常被认为是不可切除的疾病。切除腹腔干的远端胰腺切除术被描述为治疗这些肿瘤的一种新的根治性治疗概念。
报告了一名61岁女性患者的病例，该患者因伴有腹腔干浸润的局部晚期胰体癌接受了远端胰腺切除术、脾切除术及腹腔干切除术。术前对腹腔干进行了栓塞，以确保肝脏的动脉灌注。
整块切除腹腔干的远端胰腺切除术具有较高的可切除率，因此是伴有血管侵犯的局部晚期胰体癌的一种根治性选择。优化患者选择及开发有效的辅助化疗可显著提高接受该手术患者的生存率。
