MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, de Crespigny Park, Denmark Hill, London, UK.
Eur Child Adolesc Psychiatry. 2010 Sep;19(9):689-703. doi: 10.1007/s00787-010-0111-y. Epub 2010 May 11.
The worldwide history of scientific achievements in child and adolescent psychopathology is reviewed from the mid-twentieth century onwards. Attention is drawn, e.g., to diagnostic distinctions, measures of psychopathology, the several roles of epidemiological longitudinal studies, temperament and personality, developmental psychopathology, the use of 'natural experiments' to test causal inferences, environmental risks, the importance of gene-environment interplay, the relative coming together of initially diverse psychological therapies, the use of randomized-controlled trials to assess treatment efficacy, and the value and limitations of pharmacotherapy. The article ends with a look ahead to the most important opportunities and challenges for child and adolescent psychiatry, plus the hazards that need to be avoided.
本文回顾了 20 世纪中叶以来儿童和青少年精神病理学领域的全球科学成就。例如，文中提到了诊断区分、精神病理学测量、流行病学纵向研究的几个作用、气质和个性、发展精神病理学、使用“自然实验”来检验因果推断、环境风险、基因-环境相互作用的重要性、最初不同的心理治疗方法的相对融合、使用随机对照试验来评估治疗效果，以及药物治疗的价值和局限性。文章最后展望了儿童和青少年精神病学最重要的机遇和挑战，以及需要避免的危险。
