Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Avenue S., Birmingham, AL 35294, USA.
J Invest Dermatol. 2010 Jun;130(6):1496-9. doi: 10.1038/jid.2010.79.
Although infrared radiation (IRR) is ubiquitous in the terrestrial milieu, its effects on human skin have until now been largely ignored. Recent studies suggest an important role for infrared A (IRA) radiation (760-1440 nm) in dermal inflammation, photoaging, and photocarcinogenesis. In this issue, Calles et al. identify and analyze the IRA-induced transcriptome in human dermal fibroblasts. Their work paves the way for new research directions in IRA photobiology and raises important clinical questions regarding photoprotection and IRR-based dermatotherapy.
虽然红外线(IRR)在地球环境中无处不在,但它对人类皮肤的影响迄今为止在很大程度上被忽视了。最近的研究表明,红外线 A(IRA)辐射(760-1440nm)在皮肤炎症、光老化和光致癌中起着重要作用。在本期杂志中,Calles 等人鉴定并分析了人类真皮成纤维细胞中 IRA 诱导的转录组。他们的工作为 IRA 光生物学的新研究方向铺平了道路,并提出了关于光保护和基于 IRR 的皮肤治疗的重要临床问题。