Borroni Davide, Gadhvi Kunal Ajit, Hristova Rozaliya, McLean Keri, Rocha de Lossada Carlos, Romano Vito, Kaye Stephen
Ophthalmology Department, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Ophthalmology Department, University Hospital Aleksandrovska, Medical University of Sofia, Sofia, Bulgaria.
Ophthalmol Sci. 2021 Jan 13;1(1):100003. doi: 10.1016/j.xops.2021.100003. eCollection 2021 Mar.
To investigate the effect of Corneal Visualization Scheimpflug Technology tonometry (CST) on intraocular pressure (IOP).
Cohort study.
Patients with and without primary open-angle glaucoma (POAG) were included.
Intraocular pressure was measured using the Icare rebound tonometer (ICRT; Icare Finland Oy) and the biomechanically corrected IOP (bIOP) using the CST. Intraocular pressure was measured at baseline with ICRT, followed by a CST measurement in one eye with the fellow eye acting as a control. Icare measurements were repeated at 10 seconds and 1, 2, 4, 8, 15, 30, and 60 minutes in both eyes. The ratio of test eye IOP to fellow eye IOP was used to control for intrasubject variation.
Intraocular pressure change following Corneal Visualization Scheimflug Technology tonometry.
Forty participants (mean age, 54.09 ± 20.08 years) were included comprising 20 patients with POAG and 20 patients with no ocular abnormalities other than cataract. Mean central corneal thickness was similar in those without POAG (547.4 ± 55.05 μm) and with POAG (520.22 ± 37.59 μm; = 0.14). No significant change was found in IOP measured with the ICRT in the fellow eye versus the 1-hour period in either the healthy ( = 0.87) or POAG ( = 0.92) group. Significant changes were found in IOP after CST measurement for both healthy ( < 0.01) and glaucomatous ( < 0.01) eyes. After the CST measurement, the IOP reduced continuously from a mean of 13.75 mmHg to 10.84 mmHg at 4 minutes for healthy eyes and from 13.28 mmHg to 11.11 mmHg at 8 minutes for glaucomatous eyes before approaching (83% for healthy eyes and 92% POAG eyes) the pre-CST measurement at 1 hour.
Corneal Visualization Scheimpflug Technology tonometry causes a significant reduction in IOP in both glaucomatous and healthy eyes that lasts for at least 1 hour afterward.
探讨角膜可视化Scheimpflug技术眼压测量法（CST）对眼压（IOP）的影响。
队列研究。
纳入患有和未患有原发性开角型青光眼（POAG）的患者。
使用Icare回弹眼压计（ICRT；芬兰Icare公司）测量眼压，并使用CST测量生物力学校正眼压（bIOP）。在基线时用ICRT测量眼压，然后在一只眼中进行CST测量，另一只眼作为对照。双眼在10秒、1、2、4、8、15、30和60分钟时重复进行Icare测量。用测试眼眼压与对照眼眼压的比值来控制个体内差异。
角膜可视化Scheimflug技术眼压测量后眼压的变化。
纳入40名参与者（平均年龄54.09±20.08岁），包括20例POAG患者和20例除白内障外无眼部异常的患者。无POAG患者的平均中央角膜厚度（547.4±55.05μm）与POAG患者的平均中央角膜厚度（520.22±37.59μm；P = 0.14）相似。在健康组（P = 0.87）或POAG组（P = 0.92）中，对照眼用ICRT测量的眼压在1小时内与测量前相比无显著变化。健康眼（P < 0.01）和青光眼眼（P < 0.01）在CST测量后眼压均有显著变化。CST测量后，健康眼眼压从平均13.75 mmHg持续下降，4分钟时降至10.84 mmHg，青光眼眼眼压从13.28 mmHg降至8分钟时的11.11 mmHg，然后在1小时时接近CST测量前的眼压（健康眼为83%，POAG眼为92%）。
角膜可视化Scheimpflug技术眼压测量法可使青光眼眼和健康眼的眼压显著降低，且至少持续1小时。
