Baryshnikova N V
Eksp Klin Gastroenterol. 2009(7):80-2.
This article presents the results of original research, which showed that in St. Petersburg in patients with duodenal ulcer and chronic gastroduodenitis were identified more pathogenic strains of H. pylori, than in healthy voluntary infants infected with this microorganism. The most frequently detected genes, islands of H. pylori pathogenicity, in chronic gastroduodenitis--cagA and cagH, with peptic ulcer--cagA and cagE. Also found that in St. Petersburg in a greater percentage of cases circulating cagA + strains of H. pylori, as in Tajikistan. Based on these data, we can conclude that improved methods of molecular-genetic identification of H. pylori is a required condition for the optimization approaches to integrated diagnostics H. pylori-associated.
本文介绍了一项原创研究的结果，该研究表明，在圣彼得堡，十二指肠溃疡和慢性胃十二指肠炎症患者中发现的幽门螺杆菌致病菌株比感染该微生物的健康自愿者婴儿更多。在慢性胃十二指肠炎症中，最常检测到的幽门螺杆菌致病基因岛是cagA和cagH，在消化性溃疡中是cagA和cagE。还发现与塔吉克斯坦一样，圣彼得堡幽门螺杆菌cagA+菌株的流行率更高。基于这些数据，我们可以得出结论，改进幽门螺杆菌的分子遗传学鉴定方法是优化幽门螺杆菌相关综合诊断方法的必要条件。
