Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Womens Health (Larchmt). 2010 Jun;19(6):1201-7. doi: 10.1089/jwh.2009.1710.
To compare health-related quality of life (HRQOL) in those with and without metabolic syndrome in a general Iranian population.
This was a cross-sectional study of HRQOL conducted in a sample of individuals with and without metabolic syndrome using the data obtained from the Tehran Lipid and Glucose Study (TLGS) and information specifically collected for the present investigation. Metabolic syndrome was defined according to the adult treatment panel III (ATPIII) and HRQOL was assessed using the Short Form Health Survey (SF-36). Logistic regression analyses were performed for the whole sample and both sexes while adjusting for potential confounders in order to estimate odds ratios for predicting HRQOL in this population.
In all, 950 participants with (n = 361) and without (n = 589) metabolic syndrome were studied. The mean age of participants was 46.5 +/- 14.4 years. In women, but not in men, metabolic syndrome had an independent role in predicting poor HRQOL. With increase in the number of metabolic syndrome components, there was a significant decreasing trend in women's physical component summary scores.
The results indicate that metabolic syndrome is associated with poor HRQOL in women but not in men, and the association is formed mainly in relation to physical rather than mental health.
比较伊朗一般人群中患有和不患有代谢综合征者的健康相关生活质量（HRQOL）。
这是一项横断面研究，使用德黑兰血脂和血糖研究（TLGS）的数据以及专门为此项调查收集的信息，对 HRQOL 进行了有代谢综合征和无代谢综合征者的样本比较。代谢综合征根据成人治疗小组 III（ATPIII）进行定义，使用健康调查简表（SF-36）评估 HRQOL。对整个样本和男女两性进行了逻辑回归分析，调整了潜在的混杂因素，以估计在该人群中预测 HRQOL 的比值比。
共研究了 950 名患有（n = 361）和不患有（n = 589）代谢综合征的参与者。参与者的平均年龄为 46.5 ± 14.4 岁。在女性中，但不是在男性中，代谢综合征对预测 HRQOL 较差具有独立作用。随着代谢综合征成分数量的增加，女性的生理成分综合评分呈显著下降趋势。
结果表明，代谢综合征与女性的 HRQOL 较差有关，但与男性无关，这种关联主要与身体健康有关，而与心理健康无关。
