韩国人正常的 24 小时动态食管 pH 值。
Normal 24-hour Ambulatory Esophageal pH Values in Koreans.
机构信息
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
出版信息
Gut Liver. 2008 Jun;2(1):8-13. doi: 10.5009/gnl.2008.2.1.8. Epub 2008 Jun 30.
BACKGROUND/AIMS: Twenty-four-hour ambulatory esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease. The aim of this study was to quantify normal distal esophageal acid parameters in healthy Koreans.
METHODS
Thirty healthy adults who were not on medication and were free from gastrointestinal symptoms were analyzed. Ambulatory esophageal acid (pH <4) exposure parameters were recorded at 5 cm above the lower esophageal sphincter.
RESULTS
The 95th percentiles for reflux parameters assessed in the distal esophagus were as follows: percentage of total time with pH <4, 5.10%; percentage of upright time with pH <4, 7.88%; percentage of supine time with pH <4, 4.00%; number of reflux episodes, 62.7; number of reflux episodes with pH <4 for >5 minutes, 5.3; and the longest single acid-exposure episode, 21.3 minutes.
CONCLUSIONS
Physiological gastroesophageal reflux occurs frequently in healthy Koreans. These data provide a reference range that could be utilized in studies involving Korean subjects.
背景/目的：24 小时动态食管 pH 监测被认为是诊断胃食管反流病的金标准。本研究旨在量化健康韩国人正常远端食管酸参数。
方法
分析了 30 名未服用药物且无胃肠道症状的健康成年人。在食管下括约肌上方 5 厘米处记录动态食管酸（pH 值<4）暴露参数。
结果
远端食管反流参数的 95 百分位数如下：pH 值<4 的总时间百分比为 5.10%；pH 值<4 的直立时间百分比为 7.88%；pH 值<4 的仰卧时间百分比为 4.00%；反流次数为 62.7 次；pH 值<4 的反流次数持续>5 分钟为 5.3 次；最长单次酸暴露时间为 21.3 分钟。
结论
生理性胃食管反流在健康韩国人中经常发生。这些数据提供了一个参考范围，可用于涉及韩国受试者的研究。
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