儿童风湿性疾病中的巨细胞病毒感染：综述。
Cytomegalovirus infection in pediatric rheumatic diseases: a review.
机构信息
Department of Pediatrics, Hadassah-Hebrew University Medical Center, POB 24035, Mount Scopus, Jerusalem 91240, Israel.
出版信息
Pediatr Rheumatol Online J. 2010 May 20;8:17. doi: 10.1186/1546-0096-8-17.
Abstract
Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease.
摘要
人巨细胞病毒（HCMV）在儿科风湿病医生中较为熟悉，主要是作为药物免疫抑制患者机会性疾病的病因。然而，HCMV 也具有多种免疫调节作用，通过这些作用可能影响风湿性疾病的病程。本文讨论了 HCMV 与免疫系统之间的相互作用，并复习了儿童风湿性疾病患者 HCMV 感染的临床表现、诊断和治疗。
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