Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.
Am J Prev Med. 2010 Jun;38(6):575-82. doi: 10.1016/j.amepre.2010.02.015.
There is a lack of knowledge about the relationship between objectively measured physical activity and the odds of having metabolic syndrome (MetS) and cardiovascular (CVD) risk factors.
This study aims to investigate associations between accelerometer-determined steps/day and the odds of having MetS and its individual CVD risk factors in the U.S. population.
Adults in 2005-2006 NHANES with accelerometer-determined steps/day and measurements necessary to determine MetS by AHA/NHLBI were included (n=1446, 48.2% men, 33.5% with MetS, mean age=47.5 years, mean BMI=28.7 kg/m(2)). Logistic regression was used to estimate the odds of having MetS or abnormal CVD risk factors from incrementally higher levels of steps/day.
MetS prevalence decreased as steps/day increased (p<0.0001), with 55.7% of participants in the lowest categoric level of steps/day and 13.3% in the highest level having MetS. The odds of having MetS were 10% lower for each additional 1000 steps/day (OR=0.90, 95% CI=0.86, 0.93). The likelihood of having MetS was OR=0.28 (95% CI=0.18, 0.44) for active to highly active and 0.60 (0.43, 0.82) for low to somewhat-active compared to sedentary adults (p<0.0001). Adults who took more steps/day tended to have lower waist circumference, higher high-density lipoprotein (HDL) cholesterol level, and lower levels of triglycerides.
Adults who maintain an active lifestyle by accumulating more steps are likely to have a lower prevalence of MetS and its individual CVD risk factors. Although other concomitant lifestyle behaviors may influence this lower prevalence, the evidence presented here on steps/day and metabolic syndrome, and elsewhere on physical activity and other health and disease states, suggest that it is a fundamental component of daily living.
人们对于身体活动与代谢综合征（MetS）和心血管疾病（CVD）风险因素之间的关系知之甚少。
本研究旨在调查美国人群中计步器测定的步数/天与 MetS 及其个体 CVD 风险因素之间的关联。
纳入了 2005-2006 年 NHANES 中具有计步器测定的步数/天且符合 AHA/NHLBI 标准的 MetS 测量值的成年人（n=1446，48.2%为男性，33.5%患有 MetS，平均年龄为 47.5 岁，平均 BMI 为 28.7 kg/m²）。采用 logistic 回归估计从递增的步数/天水平得出患有 MetS 或异常 CVD 风险因素的几率。
随着步数/天的增加，MetS 的患病率降低（p<0.0001），在最低分类水平的步数/天中，有 55.7%的参与者患有 MetS，而在最高水平中，有 13.3%的参与者患有 MetS。每天增加 1000 步，MetS 的几率降低 10%（OR=0.90，95%CI=0.86，0.93）。与久坐不动的成年人相比，活跃至高度活跃的成年人 MetS 的几率为 0.28（95%CI=0.18，0.44），而低至有些活跃的成年人 MetS 的几率为 0.60（0.43，0.82）（p<0.0001）。每天走更多步数的成年人往往腰围更小，高密度脂蛋白（HDL）胆固醇水平更高，甘油三酯水平更低。
通过积累更多步数保持积极生活方式的成年人，MetS 及其个体 CVD 风险因素的患病率可能较低。尽管其他伴随的生活方式行为可能会影响这种较低的患病率，但此处关于步数/天和代谢综合征的证据，以及其他关于身体活动和其他健康和疾病状况的证据，表明这是日常生活的一个基本组成部分。
