Pacenta H L, Kaddoum R N, Pereiras L A, Chidiac E J, Burgoyne L L
Division of Anesthesia, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Anaesth Intensive Care. 2010 May;38(3):563-5. doi: 10.1177/0310057X1003800324.
An 18-year-old man with metastatic femoral osteosarcoma had inadequate pain control with gabapentin, naproxen and intravenous fentanyl. A tunnelled femoral nerve catheter was used to administer a continuous infusion of 0.2% ropivacaine and 4 microg/ml clonidine (10 ml/hour) until his death 88 days later During discharge from hospital, catheter disconnection resulted in severe pain and readmission. Tunnelling, aseptic insertion technique, antibiotics and sterile infusate prepared by the pharmacy may have reduced the chance of infection. We propose that this is a suitable and effective technique in the long-term management of patients with terminal cancer and should be considered on a case-by-case basis.
一名患有转移性股骨骨肉瘤的18岁男性,使用加巴喷丁、萘普生和静脉注射芬太尼后疼痛控制不佳。一根经隧道的股神经导管用于持续输注0.2%罗哌卡因和4微克/毫升可乐定(10毫升/小时),直至88天后他去世。在出院期间,导管断开导致严重疼痛并再次入院。隧道技术、无菌插入技术、抗生素以及药房配制的无菌输注液可能降低了感染几率。我们认为,这是一种适用于晚期癌症患者长期管理的有效技术,应根据具体情况予以考虑。