Department of Medicine, Faculty of Medicine, Kuwait University, Salmiya 22077, Kuwait.
Med Princ Pract. 2010;19(4):295-8. doi: 10.1159/000312716. Epub 2010 May 26.
The aim of this study was to assess the prevalence of asthma among schoolchildren and to determine the level house dust mites in Kuwaiti homes and its role in asthma and rhinitis.
The International Study of Asthma and Allergy in Children questionnaire was distributed to schoolchildren in the age group of 5-7 years, after random sampling from all the five governorates of Kuwait. The questionnaires were completed and initiated by parents with the help of the investigator and parents. House dust was collected from the bedroom floor of 549 houses in the same geographical areas where the schoolchildren were sampled, extracted and assayed for mite Der p 1 by ELISA method.
The estimated prevalence of asthma was 22.4% and that of rhinitis was 23%. House dust collected from the bedroom floor was found to contain low levels of Der p 1. There was no significant difference (p = 0.969) in the level of Der p 1 between areas in Kuwait. The highest levels of Der p 1 ranged from 0.02 to 0.10 mg/g in 3.5% of the total samples examined.
There is a high prevalence of asthma and rhinitis among the schoolchildren in Kuwait. However, the level of dust mitogens investigated in this study was below the level of concern, thus undermining their role in increasing asthma cases in Kuwait. Therefore, further studies are needed to understand the role of other mite allergens and other factors that contribute to the increased prevalence of allergic diseases in Kuwaiti children.
本研究旨在评估科威特学童哮喘的患病率,并确定家庭尘螨水平及其在哮喘和鼻炎中的作用。
对科威特五个省的所有学校进行随机抽样后,向 5-7 岁的学童发放了《儿童哮喘和过敏国际研究》问卷。在调查员和家长的帮助下,家长填写并启动了问卷。从与抽样学童相同地理区域的 549 所房屋的卧室地板上收集灰尘,并通过 ELISA 法提取和检测尘螨 Der p 1。
哮喘的估计患病率为 22.4%,鼻炎的患病率为 23%。从卧室地板上收集的灰尘中发现含有低水平的 Der p 1。科威特不同地区尘螨 Der p 1 的水平无显著差异(p = 0.969)。在检测的总样本中,有 3.5%的样本中尘螨 Der p 1 的含量最高,范围在 0.02 至 0.10mg/g。
科威特学童哮喘和鼻炎的患病率较高。然而,本研究中调查的尘螨过敏原水平低于关注水平,从而削弱了它们在增加科威特哮喘病例中的作用。因此,需要进一步研究以了解其他尘螨过敏原和导致科威特儿童过敏性疾病患病率增加的其他因素的作用。