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本地生产的即食补充食品在实际操作环境中是治疗中度急性营养不良的有效方法。

Locally produced ready-to-use supplementary food is an effective treatment of moderate acute malnutrition in an operational setting.

作者信息

Lagrone L, Cole S, Schondelmeyer A, Maleta K, Manary M J

机构信息

Department of Pediatrics, Washington University, St Louis, USA.

出版信息

Ann Trop Paediatr. 2010;30(2):103-8. doi: 10.1179/146532810X12703901870651.

Abstract

BACKGROUND

Typical treatment of moderate acute malnutrition, simple wasting, in sub-Saharan Africa consists of dietary counselling and/or general or targeted distribution of corn/soy-blended flour (CSB). A randomised clinical effectiveness trial in 2007 showed CSB to be less effective than ready-to-use supplementary food (RUSF).

AIM

To determine the operational effectiveness of treating moderate acute malnutrition with RUSF.

METHODS

Children aged 6-59 months were recruited in rural southern Malawi. Each child received 65 kcal/kg/d of locally produced soy/peanut RUSF, a product that provided about 1 RDA of each micronutrient. Anthropometric measurements were taken every 2 weeks and additional rations of RUSF were distributed at this time if the child remained wasted. Study participation lasted up to 8 weeks.

RESULTS

Of the 2417 children enrolled, 80% recovered, 4% defaulted, 0.4% died, 12% remained moderately wasted and 3% developed severe acute malnutrition. Weight, length and MUAC gain were 2.6 g/kg/d, 0.2 mm/d and 0.1 mm/d respectively. Cost per child treated was $5.39.

CONCLUSIONS

This intervention proved to be robust, maintaining high recovery rates and low default rates when instituted without the additional supervision and beneficiary incentives of a research setting.

摘要

背景

在撒哈拉以南非洲,中度急性营养不良(单纯消瘦)的典型治疗方法包括饮食咨询和/或玉米/大豆混合粉(CSB)的常规或定向分发。2007年的一项随机临床疗效试验表明,CSB的效果不如即食补充食品(RUSF)。

目的

确定使用RUSF治疗中度急性营养不良的实际效果。

方法

在马拉维南部农村招募6至59个月大的儿童。每个儿童每天接受65千卡/千克的当地生产的大豆/花生RUSF,该产品提供每种微量营养素约1个推荐膳食摄入量。每2周进行一次人体测量,如果儿童仍消瘦,则此时额外分发RUSF口粮。研究参与持续长达8周。

结果

在登记的2417名儿童中,80%康复,4%退出,0.4%死亡,12%仍为中度消瘦,3%发展为重度急性营养不良。体重、身长和上臂围的增加分别为2.6克/千克/天、0.2毫米/天和0.1毫米/天。每个接受治疗的儿童的费用为5.39美元。

结论

该干预措施被证明是有效的,在没有研究环境中的额外监督和受益激励措施的情况下实施时,保持了高康复率和低退出率。

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