Brady Bobbi Georgia, Ortleb Melanie, Boyd Alan S, Powers Jennifer
Vanderbilt University.
J Clin Aesthet Dermatol. 2015 Nov;8(11):49-52.
Cutaneous collagenous vasculopathy is a rare microangiopathy of dermal blood vessels. Clinically indistinguishable from generalized essential telangiectasia, this condition is diagnosed by its unique histological appearance. In contrast to other primary telangiectatic processes, cutaneous collagenous vasculopathy has dilated vascular structures that contain deposits of eosinophilic hyaline material within the vessel walls. To date, cutaneous collagenous vasculopathy has been described in a total of 19 cases in the medical literature. The first several cases were described exclusively in middle-aged to elderly men. Though it has now been described in both men and women, cutaneous collagenous vasculopathy is still most often described in middle-aged to older adults. No particular disease or medication has been linked to the development of cutaneous collagenous vasculopathy, and the etiology remains unknown. In this case series, the authors present three additional patients diagnosed with cutaneous collagenous vasculopathy and discuss their clinical and histopathologic features.
皮肤胶原性血管病是一种罕见的真皮血管微血管病。临床上与全身性特发性毛细血管扩张难以区分，该病通过其独特的组织学表现得以诊断。与其他原发性毛细血管扩张性疾病不同，皮肤胶原性血管病的血管结构扩张，血管壁内含有嗜酸性透明物质沉积。迄今为止，医学文献中总共描述了19例皮肤胶原性血管病。最初的几例仅在中年至老年男性中被描述。尽管现在已在男性和女性中均有描述，但皮肤胶原性血管病仍最常出现在中年至老年成年人中。没有特定疾病或药物与皮肤胶原性血管病的发生有关，其病因仍然不明。在这个病例系列中，作者介绍了另外三名被诊断为皮肤胶原性血管病的患者，并讨论了他们的临床和组织病理学特征。
