Bailey Regan L, McDowell Margaret A, Dodd Kevin W, Gahche Jaime J, Dwyer Johanna T, Picciano Mary Frances
Office of Dietary Supplements, National Institutes of Health, Bethesda, MD, USA.
Am J Clin Nutr. 2010 Aug;92(2):353-8. doi: 10.3945/ajcn.2010.29652. Epub 2010 Jun 9.
Total folate intake includes naturally occurring food folate and folic acid from fortified foods and dietary supplements. Recent reports have focused on total folate intakes of persons aged > or =14 y. Information on total folate intakes of young children, however, is limited.
The objective was to compute total folate and total folic acid intakes of US children aged 1-13 y by using a statistical method that adjusts for within-person variability and to compare these intakes with the Dietary Reference Intake guidelines for adequacy and excess.
Data from the 2003-2006 National Health and Nutrition Examination Survey, a nationally representative cross-sectional survey, were analyzed. Total folate intakes were derived by combining intakes of food folate (naturally occurring and folic acid from fortified foods) on the basis of 24-h dietary recall results and folic acid intakes from dietary supplements on the basis of a 30-d questionnaire.
More than 95% of US children consumed at least the Estimated Average Requirement (EAR) for folate from foods alone. More than one-third (35%) of US children aged 1-13 y used dietary supplements, and 28% used dietary supplements containing folic acid. Supplement users had significantly higher total folate and folic acid intakes than did nonusers. More than half (53%) of dietary supplement users exceeded the Tolerable Upper Intake Level (UL) for total folic acid (fortified food + supplements) as compared with 5% of nonusers.
Total folate intakes of most US children aged 1-13 y meet the EAR. Children who used dietary supplements had significantly higher total folate intakes and exceeded the UL by >50%.
总叶酸摄入量包括天然食物叶酸以及强化食品和膳食补充剂中的叶酸。近期报告主要关注年龄≥14岁人群的总叶酸摄入量。然而,关于幼儿总叶酸摄入量的信息有限。
采用一种针对个体内变异性进行调整的统计方法,计算美国1至13岁儿童的总叶酸和总叶酸酸摄入量,并将这些摄入量与膳食参考摄入量的充足和过量指南进行比较。
分析了2003 - 2006年全国健康和营养检查调查的数据,这是一项具有全国代表性的横断面调查。总叶酸摄入量通过结合基于24小时膳食回忆结果的食物叶酸(天然存在的和强化食品中的叶酸)摄入量以及基于30天问卷的膳食补充剂中的叶酸酸摄入量得出。
超过95%的美国儿童仅从食物中摄入的叶酸至少达到估计平均需求量(EAR)。1至13岁的美国儿童中有超过三分之一(35%)使用膳食补充剂,28%使用含叶酸的膳食补充剂。补充剂使用者的总叶酸和叶酸酸摄入量显著高于非使用者。膳食补充剂使用者中超过一半(53%)的人总叶酸酸(强化食品 + 补充剂中)摄入量超过可耐受最高摄入量(UL),而非使用者中这一比例为五分之一(5%)。
大多数美国1至13岁儿童的总叶酸摄入量达到EAR。使用膳食补充剂的儿童总叶酸摄入量显著更高,且超过UL的比例超过50%。