Department of Community Health, Brown University Program in Public Health, Providence, RI 02912, USA.
Psychol Addict Behav. 2010 Jun;24(2):349-54. doi: 10.1037/a0018332.
Previous randomized controlled trials have not supported moderate intensity exercise as an efficacious adjunct to smoking cessation treatments for women; however, compliance with exercise programs in these studies has been poor. The purpose of this pilot study was to estimate the effects of moderate intensity exercise on smoking cessation outcomes under optimal conditions for exercise program compliance. Sixty previously sedentary, healthy, female smokers were randomized to an 8-week program consisting of brief baseline smoking cessation counseling and the nicotine patch plus either 150 min/week of moderate intensity exercise or contact control. Participants attended a median of 86.4% and 95.5% of prescribed exercise/control sessions, respectively. There was a moderate, though statistically nonsignificant, effect of exercise at post-treatment for objectively verified 7-day point prevalence abstinence (48.3% vs. 23.3%; OR = 3.07, 95% CI: 0.89-11.07) and prolonged abstinence (34.5% vs. 20.0%; OR = 2.11, 95% CI: 0.56-8.32). Effects were attenuated when controlling for potential confounders, and after a 1-month, no-treatment period. The findings provide a preliminary indication that, given adequate compliance, moderate intensity exercise may enhance short-term smoking cessation outcomes for women; however, a larger trial is warranted.
先前的随机对照试验并未支持中等强度运动作为女性戒烟治疗的有效辅助手段；然而，这些研究中的运动计划的依从性一直很差。本研究的目的是在运动计划依从性的最佳条件下，评估中等强度运动对戒烟结果的影响。60 名先前久坐不动、健康的女性吸烟者被随机分为 8 周的计划，包括简短的基线戒烟咨询和尼古丁贴片，以及每周 150 分钟的中等强度运动或联系对照组。参与者分别平均参加了 86.4%和 95.5%的规定运动/对照组会议。尽管统计学上无显著意义，但在治疗后，运动对客观验证的 7 天点患病率戒烟（48.3%对 23.3%；OR=3.07，95%CI：0.89-11.07）和延长戒烟（34.5%对 20.0%；OR=2.11，95%CI：0.56-8.32）有适度影响。当控制潜在混杂因素以及 1 个月无治疗期后，效果减弱。这些发现初步表明，在充分依从的情况下，中等强度运动可能会增强女性短期戒烟的效果；然而，还需要更大的试验。
