• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

临床综述:在 ICU 中尸检的作用是什么?

Clinical review: What is the role for autopsy in the ICU?

机构信息

Department of General Internal Medicine, Medical Intensive Care Unit, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.

出版信息

Crit Care. 2010;14(2):221. doi: 10.1186/cc8925.

DOI:10.1186/cc8925
PMID:20565845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3226293/
Abstract

The availability of advanced diagnostic tools has grown in the past decades. Hence, a growing false belief exists that everything is known about the patient before death. Moreover, intensivists may wrongly believe that autopsy findings do not contribute to the understanding of pathophysiological events. The immediate result is that few ICUs nowadays assemble enough autopsy cases with new and interesting clinicopathological features. However, we believe that, at least in tertiary ICUs, autopsies remain a valuable examination, as a tool for quality control, as a way of establishing gold standards for diagnostic examinations and as an aid in developing guidelines for treatment and diagnosis of diseases frequently encountered in the ICU. Finally, due to the ever-expanding armamentarium of immunosuppressive agents, a growing list of opportunistic infections is discovered during autopsy. The present article gives an overview of autopsy studies conducted in the ICU and discusses the pros and cons of performing these.

摘要

在过去的几十年中,先进的诊断工具变得越来越普及。因此,人们逐渐产生了一种错误的信念,认为在患者死亡之前,已经对其了如指掌。此外,重症监护医生可能错误地认为尸检结果对理解病理生理事件没有帮助。其直接后果是,现在很少有 ICU 能够收集到足够的具有新的有趣临床病理特征的尸检病例。然而,我们认为,至少在三级 ICU 中,尸检仍然是一种有价值的检查手段,可作为质量控制的工具、建立诊断检查金标准的方法,以及协助制定 ICU 中常见疾病的治疗和诊断指南。最后,由于免疫抑制剂的不断增加,尸检过程中发现了越来越多的机会性感染。本文概述了 ICU 中进行的尸检研究,并讨论了进行这些研究的利弊。

相似文献

1
Clinical review: What is the role for autopsy in the ICU?临床综述:在 ICU 中尸检的作用是什么?
Crit Care. 2010;14(2):221. doi: 10.1186/cc8925.
2
Virtual autopsy as an alternative to traditional medical autopsy in the intensive care unit: a prospective cohort study.重症监护病房中传统医学尸检的替代方法:一项前瞻性队列研究。
Ann Intern Med. 2012 Jan 17;156(2):123-30. doi: 10.7326/0003-4819-156-2-201201170-00008.
3
Association of pre mortem diagnosis and autopsy findings in pediatric intensive care unit versus emergency department versus ward patients.儿科重症监护病房、急诊科和病房患者的生前诊断与尸检结果的关联
Crit Care Med. 1996 Apr;24(4):683-6. doi: 10.1097/00003246-199604000-00022.
4
Clinical and autopsy diagnoses in the intensive care unit: a prospective study.重症监护病房的临床诊断与尸检诊断:一项前瞻性研究。
Arch Intern Med. 2004 Feb 23;164(4):389-92. doi: 10.1001/archinte.164.4.389.
5
Do autopsies of critically ill patients reveal important findings that were clinically undetected?对重症患者进行尸检是否能揭示临床上未被发现的重要发现?
Crit Care Med. 1998 Aug;26(8):1332-6. doi: 10.1097/00003246-199808000-00015.
6
Post mortem examination in the intensive care unit: still useful?重症监护病房中的尸检:仍然有用吗?
Intensive Care Med. 2004 Nov;30(11):2080-5. doi: 10.1007/s00134-004-2448-5. Epub 2004 Oct 7.
7
Diagnostic errors in the intensive care unit: a systematic review of autopsy studies.重症监护病房的诊断错误:尸体解剖研究的系统评价。
BMJ Qual Saf. 2012 Nov;21(11):894-902. doi: 10.1136/bmjqs-2012-000803. Epub 2012 Jul 21.
8
Characteristics of discrepancies between clinical and autopsy diagnoses in the intensive care unit: a 5-year review.重症监护病房临床诊断与尸检诊断差异的特征:一项为期5年的回顾。
Intensive Care Med. 2003 Feb;29(2):321-4. doi: 10.1007/s00134-002-1576-z. Epub 2002 Nov 30.
9
[The evaluation of autopsy in the pediatric intensive unit].[儿科重症监护病房尸体解剖的评估]
An Esp Pediatr. 1997 Mar;46(3):224-8.
10
[Errors in autopsy in Germany. Results of a multicenter study (II)].[德国尸检中的错误。一项多中心研究的结果(II)]
Arch Kriminol. 1997 Mar-Apr;199(3-4):65-74.

引用本文的文献

1
The impact of autopsy participation on clinical residency.尸检参与对临床住院医师培训的影响。
J Gen Fam Med. 2021 May 3;22(5):278-287. doi: 10.1002/jgf2.449. eCollection 2021 Sep.
2
Clinical diagnoses vs. autopsy findings in early deceased septic patients in the intensive care: a retrospective cohort study.临床诊断与重症监护中早期死亡脓毒症患者的尸检结果比较:一项回顾性队列研究。
Virchows Arch. 2021 Jun;478(6):1173-1178. doi: 10.1007/s00428-020-02984-5. Epub 2020 Dec 11.
3
A Pathophysiological Insight into Sepsis and Its Correlation with Postmortem Diagnosis.脓毒症的病理生理学见解及其与死后诊断的相关性
Mediators Inflamm. 2016;2016:4062829. doi: 10.1155/2016/4062829. Epub 2016 Apr 27.
4
Postmortem CT is more accurate than clinical diagnosis for identifying the immediate cause of death in hospitalized patients: a prospective autopsy-based study.在确定住院患者的直接死因方面,尸检CT比临床诊断更准确:一项基于前瞻性尸检的研究。
Virchows Arch. 2016 Jul;469(1):101-9. doi: 10.1007/s00428-016-1937-6. Epub 2016 Apr 16.
5
Infective and non-infective endocarditis in critically ill patients: a clinical-pathological study.重症患者感染性与非感染性心内膜炎:一项临床病理研究
Intern Emerg Med. 2014 Oct;9(7):773-8. doi: 10.1007/s11739-014-1054-y. Epub 2014 Feb 12.
6
Who is at risk for diagnostic discrepancies? Comparison of pre- and postmortal diagnoses in 1800 patients of 3 medical decades in East and West Berlin.哪些人存在诊断差异的风险?对东、西柏林 3 个医学年代的 1800 名患者的生前和死后诊断进行比较。
PLoS One. 2012;7(5):e37460. doi: 10.1371/journal.pone.0037460. Epub 2012 May 22.
7
Preventable mortality evaluation in the ICU.重症监护病房中可预防死亡率的评估
Crit Care. 2012 Dec 12;16(2):309. doi: 10.1186/cc11212.
8
Is routine autopsy in the intensive care unit viable? Authors' response.重症监护病房中的常规尸检可行吗?作者回应。
Crit Care. 2010;14(4):433. doi: 10.1186/cc9194. Epub 2010 Jul 29.
9
The role for autopsy in the intensive care unit: technological considerations.尸检在重症监护病房中的作用:技术考量
Crit Care. 2010;14(4):426. doi: 10.1186/cc9075. Epub 2010 Jul 5.
10
Is routine autopsy in the intensive care unit viable?重症监护病房的常规尸检可行吗?
Crit Care. 2010;14(3):425. doi: 10.1186/cc9069. Epub 2010 Jun 30.

本文引用的文献

1
Lung pathology in fatal novel human influenza A (H1N1) infection.新型致命性人感染甲型 H1N1 流感的肺部病理学改变。
Am J Respir Crit Care Med. 2010 Jan 1;181(1):72-9. doi: 10.1164/rccm.200909-1420OC. Epub 2009 Oct 29.
2
Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1) - United States, May-August 2009.2009年甲型H1N1流感大流行致死病例肺组织标本中的细菌合并感染 - 美国,2009年5月至8月
MMWR Morb Mortal Wkly Rep. 2009 Oct 2;58(38):1071-4.
3
Glucose control in the intensive care unit: a roller coaster ride or a swinging pendulum?重症监护病房中的血糖控制:是过山车之旅还是摆动的钟摆?
Ann Intern Med. 2009 Jun 2;150(11):809-11. doi: 10.7326/0003-4819-150-11-200906020-00009.
4
Significance of the isolation of Candida species from airway samples in critically ill patients: a prospective, autopsy study.危重症患者气道样本中念珠菌属分离的意义:一项前瞻性尸检研究。
Intensive Care Med. 2009 Sep;35(9):1526-31. doi: 10.1007/s00134-009-1482-8. Epub 2009 Apr 9.
5
Intensive versus conventional glucose control in critically ill patients.危重症患者强化血糖控制与常规血糖控制的比较
N Engl J Med. 2009 Mar 26;360(13):1283-97. doi: 10.1056/NEJMoa0810625. Epub 2009 Mar 24.
6
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.念珠菌病管理临床实践指南:美国传染病学会2009年更新版
Clin Infect Dis. 2009 Mar 1;48(5):503-35. doi: 10.1086/596757.
7
The vanishing nonforensic autopsy.逐渐消失的非法医尸检。
N Engl J Med. 2008 Feb 28;358(9):873-5. doi: 10.1056/NEJMp0707996.
8
Premortem clinical diagnoses and postmortem autopsy findings: discrepancies in critically ill cancer patients.临终前临床诊断与尸检结果:重症癌症患者中的差异
Crit Care. 2007;11(2):R48. doi: 10.1186/cc5782.
9
Comparison of clinical and post-mortem findings in intensive care unit patients.重症监护病房患者临床与尸检结果的比较。
Virchows Arch. 2007 Mar;450(3):329-33. doi: 10.1007/s00428-006-0364-5. Epub 2007 Jan 25.
10
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease.那他珠单抗治疗克罗恩病后发生的进行性多灶性白质脑病。
N Engl J Med. 2005 Jul 28;353(4):362-8. doi: 10.1056/NEJMoa051586. Epub 2005 Jun 9.