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显微镜细胞图像中的细胞核分割:一个手动分割的数据集及算法比较

NUCLEAR SEGMENTATION IN MICROSCOPE CELL IMAGES: A HAND-SEGMENTED DATASET AND COMPARISON OF ALGORITHMS.

作者信息

Coelho Luís Pedro, Shariff Aabid, Murphy Robert F

机构信息

Lane Center for Computational Biology, Carnegie Mellon University.

出版信息

Proc IEEE Int Symp Biomed Imaging. 2009;5193098:518-521. doi: 10.1109/ISBI.2009.5193098.

DOI:10.1109/ISBI.2009.5193098
PMID:20628545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2901896/
Abstract

Image segmentation is an essential step in many image analysis pipelines and many algorithms have been proposed to solve this problem. However, they are often evaluated subjectively or based on a small number of examples. To fill this gap, we hand-segmented a set of 97 fluorescence microscopy images (a total of 4009 cells) and objectively evaluated some previously proposed segmentation algorithms.We focus on algorithms appropriate for high-throughput settings, where only minimal user intervention is feasible.The hand-labeled dataset (and all software used to compare methods) is publicly available to enable others to use it as a benchmark for newly proposed algorithms.

摘要

图像分割是许多图像分析流程中的关键步骤,人们已经提出了许多算法来解决这个问题。然而,这些算法的评估往往是主观的,或者基于少量示例。为了填补这一空白,我们手工分割了一组97张荧光显微镜图像(共4009个细胞),并对一些先前提出的分割算法进行了客观评估。我们专注于适用于高通量设置的算法,在这种设置下,只进行最少的用户干预是可行的。手工标记的数据集(以及用于比较方法的所有软件)是公开可用的,以便其他人将其用作新提出算法的基准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8859/2901896/db195e100296/nihms212403f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8859/2901896/db195e100296/nihms212403f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8859/2901896/db195e100296/nihms212403f1.jpg

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