健康生物标志物在应激和衰老研究中的应用前沿。
Frontiers in the use of biomarkers of health in research on stress and aging.
机构信息
Department of Human Development and Family Studies, Pennsylvania State University, 118 Henderson Building, University Park, PA 16802, USA.
出版信息
J Gerontol B Psychol Sci Soc Sci. 2010 Sep;65(5):513-25. doi: 10.1093/geronb/gbq049. Epub 2010 Jul 20.
Abstract
Assessment of biomarkers that reflect objective indicators of physiological processes has become increasingly popular in psychological research on stress and aging. The current article reviews biomarkers of the neuroendocrine and immune systems, including issues related to measurement and normative age-related changes. We also discuss how exposure to stressors can provoke changes in these biomarkers and propose that stressful experiences may accelerate age-related declines in these systems. We recommend that future research examining physical health and aging incorporate dynamic and multivariate methods for assessing links between stressors and biomarkers.
摘要
评估反映生理过程客观指标的生物标志物在压力和衰老的心理学研究中变得越来越流行。本文综述了神经内分泌和免疫系统的生物标志物，包括与测量和与年龄相关的正常变化有关的问题。我们还讨论了应激源如何引发这些生物标志物的变化，并提出应激经历可能加速这些系统的与年龄相关的衰退。我们建议未来研究身体健康和衰老时采用动态和多变量的方法来评估应激源与生物标志物之间的联系。
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本文引用的文献
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