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越南孕妇贫血、地中海贫血和缺铁相关负担。

Burden of anemia in relation to thalassemia and iron deficiency among Vietnamese pregnant women.

机构信息

Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.

出版信息

Acta Haematol. 2013;130(4):281-7. doi: 10.1159/000351168. Epub 2013 Aug 20.

Abstract

BACKGROUND AND AIMS

Information about the extent to which anemia is related to thalassemia and iron deficiency (ID) is not available in Vietnam. This study investigated the burden of anemia in relation to thalassemia and ID among Vietnamese pregnant women.

METHODS

A cross-sectional study was conducted in Thua Thien Hue, Central Vietnam. Blood samples taken from 399 pregnant women with a gestational age <12 weeks were analyzed. Anemia was defined as Hb levels <11 g/dl, and ID as ferritin values <15 ng/ml.

RESULTS

Out of 399 participants, 77 (19.3%) were anemic. While the prevalence of ID was 20.1%, the prevalence of ID anemia was 6.0%. The overall prevalence of thalassemia was 7.3%. Of the 77 anemic women, 24 (31.2%) had ID, and 20 (26.0%) had thalassemia genes. The rest (42.9%) were anemic due to unknown causes.

CONCLUSIONS

The results indicate that ID remains a significant health burden among the study population, together with anemia caused by unknown factors. Thalassemias appear not to contribute to a great extent to anemia among Vietnamese pregnant women. Other causes need to be investigated further in order to develop an effective control program for anemia within the population.

摘要

背景与目的

在越南,有关贫血与地中海贫血和缺铁(ID)之间关系的信息尚不清楚。本研究调查了贫血与越南孕妇地中海贫血和 ID 之间的关系。

方法

在中越顺化省进行了一项横断面研究。对 399 名孕龄<12 周的孕妇进行了血液样本分析。贫血定义为 Hb 水平<11 g/dl,ID 定义为铁蛋白值<15 ng/ml。

结果

在 399 名参与者中,有 77 名(19.3%)贫血。ID 的患病率为 20.1%,ID 性贫血的患病率为 6.0%。地中海贫血的总患病率为 7.3%。在 77 名贫血妇女中,24 名(31.2%)有 ID,20 名(26.0%)有地中海贫血基因。其余(42.9%)因不明原因贫血。

结论

结果表明,ID 仍然是研究人群中的一个重大健康负担,同时还有不明原因引起的贫血。地中海贫血似乎没有在很大程度上导致越南孕妇贫血。需要进一步调查其他原因,以便为该人群制定有效的贫血控制计划。

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