Matsuda Takahisa, Parra-Blanco Adolfo, Saito Yutaka, Sakamoto Taku, Nakajima Takeshi
Endoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Gastrointest Endosc Clin N Am. 2010 Jul;20(3):487-96. doi: 10.1016/j.giec.2010.03.007.
Although of lower prevalence compared with polypoid neoplasms, the non-polypoid neoplasms, especially the depressed type, are important to diagnose because they belong to a distinct biologically aggressive subset, given the high rate of intramucosal or submucosal cancers. The detection and diagnosis of the non-polypoid colorectal neoplasm presents a challenge and an opportunity. Above all, characteristic colonoscopic findings obtained by a combination of conventional colonoscopy and magnifying chromoendoscopy are useful for determination of the invasion depth of non-polypoid colorectal cancers, an essential factor in selecting a treatment modality.
尽管与息肉样肿瘤相比，非息肉样肿瘤的患病率较低，但非息肉样肿瘤，尤其是凹陷型，因其黏膜内或黏膜下癌的发生率高，属于生物学上具有侵袭性的独特亚型，所以诊断很重要。非息肉样结直肠肿瘤的检测和诊断既带来了挑战，也提供了机遇。最重要的是，通过传统结肠镜检查和放大色素内镜检查相结合获得的特征性结肠镜检查结果，有助于确定非息肉样结直肠癌的浸润深度，这是选择治疗方式的一个关键因素。
