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英国立法变更前,在学校和学院/大学学生中使用麦角酸二乙酰胺及相关不良反应。

Mephedrone use and associated adverse effects in school and college/university students before the UK legislation change.

机构信息

Clinical Toxicology, Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK.

出版信息

QJM. 2010 Nov;103(11):875-9. doi: 10.1093/qjmed/hcq134. Epub 2010 Jul 30.

Abstract

BACKGROUND

Mephedrone is a synthetic cathinone that is commonly used as a recreational drug among those who attend nightclubs. There have been increasing reports of toxicity associated with its use and it was controlled as a Class B drug under the Misuse of Drugs Act (1971) in the UK on 16 April 2010. There has been a suggestion from media reports that mephedrone use is common in children/students but there is no data on the prevalence of its use among the general population. The aim of this study was to determine the prevalence and frequency of use of mephedrone among school and college/university aged individuals and to collect data on the sources of mephedrone and acute harm related to its use.

METHODS

Data was collected using a questionnaire survey in schools, colleges and universities in the Tayside area of Scotland, UK in February 2010.

RESULTS

A total of 1006 individuals completed the survey [501 (49.8%) males and 505 (50.2%) females], of whom 349 classified their educational institute as a school and 657 as a college/university. Among them 205 (20.3%) reported previous use of mephedrone; 23.4% reported using only using mephedrone on one occasion previously, although 4.4% reported daily use. A total of 56% of those who had used mephedrone, reported at least one unwanted effect associated with its use. A total of 17.6% of users reported 'addiction or dependence' symptoms associated with their mephedrone use. A total of 48.8% of users sourced mephedrone from street level dealers, 10.7% from the Internet.

CONCLUSION

We have shown in this study that the use of mephedrone among school and college/university students is common and that users found it easy to obtain. There was a high prevalence of unwanted effects associated with its use. Further work is needed to determine the impact of the recent changes in the UK legislation relating to mephedrone and other related cathinones and whether this has been effective in reducing the prevalence of mephedrone use.

摘要

背景

甲卡西酮是一种常见的在夜总会中被滥用的合成卡西酮类药物。随着其使用导致的中毒案例不断增多,英国在 2010 年 4 月 16 日将其纳入 1971 年《滥用毒品法》(Misuse of Drugs Act 1971)管制的 B 类药物。媒体报道称,甲卡西酮在儿童/学生中使用普遍,但尚无其在普通人群中使用的流行率数据。本研究旨在确定学校和学院/大学年龄段个体中甲卡西酮的使用频率和流行率,并收集有关甲卡西酮来源及其使用相关的急性危害的数据。

方法

2010 年 2 月,在苏格兰泰赛德地区的学校、学院和大学使用问卷调查收集数据。

结果

共有 1006 人完成了调查[501 名(49.8%)男性和 505 名(50.2%)女性],其中 349 人将其教育机构归类为学校,657 人归类为学院/大学。其中 205 人(20.3%)报告过去曾使用过甲卡西酮;23.4%的人报告之前只使用过一次甲卡西酮,尽管 4.4%的人报告每天使用。总共 56%的使用过甲卡西酮的人报告说,使用过程中出现了至少一种不良影响。共有 17.6%的使用者报告与使用甲卡西酮相关的“成瘾或依赖”症状。共有 48.8%的使用者从街头毒贩处获得甲卡西酮,10.7%的使用者从互联网获得。

结论

在这项研究中,我们表明,在学校和学院/大学学生中使用甲卡西酮很常见,而且使用者很容易获得。使用过程中出现不良影响的比例很高。需要进一步开展工作,以确定英国最近对甲卡西酮和其他相关苯丙胺类药物的立法变更的影响,以及这是否有效降低了甲卡西酮的使用频率。

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