Freitas Ruffo, Freitas Nilceana Maya Aires, Curado Maria Paula, Martins Edesio, Silva Carleane Maciel Bandeira, Rahal Rosemar Macedo Sousa, Queiroz Geraldo Silva
Goiás Mastology Research Network, Goiânia, Goiás, Brazil.
Sao Paulo Med J. 2010;128(2):81-4. doi: 10.1590/s1516-31802010000200007.
It has been suggested that there has been a large increase in breast cancer incidence among young women over the last decade. The aim of this study was to describe the incidence of breast cancer among young women up to 39 years of age in Goiânia, between 1988 and 2003, and to compare this with other age groups.
Retrospective study using the database of the Population-based Cancer Registry of Goiânia, State of Goiás, Brazil.
The incidence was calculated according to age groups: up to 39 years, 40 to 59 years and 60 years and over. Average annual percentage changes (AAPCs) were estimated for the different age groups using Poisson regression.
Over this period, 3,310 new cases were recorded. The standardized incidence was 2.89/100,000 in 1988 and increased to 6.37/100,000 in 2003 (R(2) = 0.52) for the group aged up to 39 years (p < 0.003). For the group from 40 to 59 years old, the incidence was 14.39/100,000 in 1988 and 41.70/100,000 in 2003 (R(2) = 0.85; p < 0.001). For the group aged 60 years and over, it was 17.62/100,000 and 28.49/100,000, respectively (R(2) = 0.67; p < 0.001). The AAPCs were 5.22%, 5.53% and 4.54% for the age groups up to 39, 40 to 59 and 60 years and over, respectively.
The incidence of breast cancer among young women in Goiânia has been increasing significantly, although this change was similar to the increase in other age groups.
有人认为在过去十年中，年轻女性乳腺癌发病率大幅上升。本研究旨在描述1988年至2003年间戈亚尼亚市39岁及以下年轻女性乳腺癌的发病率，并与其他年龄组进行比较。
采用巴西戈亚斯州戈亚尼亚市基于人群的癌症登记数据库进行回顾性研究。
根据年龄组计算发病率：39岁及以下、40至59岁和60岁及以上。使用泊松回归估计不同年龄组的年均百分比变化（AAPC）。
在此期间，共记录了3310例新病例。39岁及以下年龄组的标准化发病率在1988年为2.89/10万，2003年增至6.37/10万（R² = 0.52）（p < 0.003）。40至59岁年龄组的发病率在1988年为14.39/10万，2003年为41.70/10万（R² = 0.85；p < 0.001）。60岁及以上年龄组的发病率分别为17.62/10万和28.49/10万（R² = 0.67；p < 0.001）。39岁及以下、40至59岁和60岁及以上年龄组的AAPC分别为5.22%、5.53%和4.54%。
戈亚尼亚市年轻女性乳腺癌发病率显著上升，尽管这一变化与其他年龄组的上升情况相似。
