Crooks V, Waller S, Smith T, Hahn T J
Geriatric Research, Education and Clinical Center, VA Medical Center, West Los Angeles.
J Gerontol. 1991 Jul;46(4):M139-44. doi: 10.1093/geronj/46.4.m139.
The Karnofsky Performance Scale (KPS) was evaluated in a geriatric outpatient population with regard to three issues: its strength of association with widely used and validated geriatric instruments; its ability to predict patient outcomes; and its ability to serve as an identifier of high-risk patients. The 134-patient sample was given a comprehensive geriatric assessment which included the KPS, the Activities of Daily Living (ADL) scale, the Instrumental Activities of Daily Living (IADL) scale, and other psychosocial and sensory tests. The KPS, ADL, and IADL were significantly correlated with each other, and the KPS showed the strongest associations with other functional measures. The KPS was also highly predictive of outcomes, performing better or equally well as the ADL and IADL. The KPS designation of high- and low-risk groups resulted in statistically significant score differences between groups in all but one assessment area, demonstrating better ability to discriminate than either the ADL or IADL. Thus, the KPS was shown to serve as an effective proxy score for a patient's health and functional status. It also was a significant predictor of hospitalizations, survival time, community residence, and institutionalization. Finally, the KPS was shown to adequately distinguish risk groups to aid in the targeting of services to ambulatory geriatric patients.
在老年门诊人群中对卡氏功能状态评分量表（KPS）进行了三方面评估：其与广泛使用且经过验证的老年评估工具的关联强度；其预测患者预后的能力；以及其作为高危患者识别工具的能力。对134名患者的样本进行了全面的老年评估，其中包括KPS、日常生活活动能力（ADL）量表、工具性日常生活活动能力（IADL）量表以及其他心理社会和感官测试。KPS、ADL和IADL之间存在显著相关性，且KPS与其他功能测量指标的关联最为紧密。KPS对预后也具有高度预测性，其表现优于或等同于ADL和IADL。KPS对高危和低危组的划分在除一个评估领域外的所有领域中均导致组间得分存在统计学显著差异，表明其区分能力优于ADL或IADL。因此，KPS被证明是患者健康和功能状态的有效替代评分。它也是住院、生存时间、社区居住和机构化的重要预测指标。最后，KPS被证明能够充分区分风险组，以帮助针对门诊老年患者提供服务。
