Kim Grace K, Del Rosso James Q
J Clin Aesthet Dermatol. 2010 Jan;3(1):32-8.
Psoriasis is a commonly encountered dermatosis with a variety of internal and external paradoxical factors contributing to the clinical course of the disease. There are several drugs described in the literature that have been associated with the initiation, exacerbation, and aggravation of psoriasis. Understanding the pathophysiology can provide clues to treatment and management of drug-induced and drug-aggravated psoriasis, which may be indistinguishable from idiopathic psoriasis. The clinical manifestations of drug-associated psoriasis can range from plaque-type psoriasis to severe erythroderma, thus warranting astute and sustained clinical observation.
银屑病是一种常见的皮肤病，多种内在和外在的矛盾因素影响着该疾病的临床病程。文献中描述了几种与银屑病的发生、加重及恶化相关的药物。了解其病理生理学可为药物性银屑病和药物加重性银屑病的治疗与管理提供线索，这两种情况可能与特发性银屑病难以区分。药物相关性银屑病的临床表现范围从斑块型银屑病到严重的红皮病，因此需要敏锐且持续的临床观察。
