Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China.
Org Lett. 2010 Sep 17;12(18):4014-7. doi: 10.1021/ol1016228.
N,N-dimethyl-N-(pyrenyl-1-methyl) dodecan-1-ammonium has been designed and applied as a fluorescent probe for sensing bacterial endotoxin. Upon assembly with bacterial endotoxin (lipopolysaccharide) in aqueous solution, the probe exhibits a ratiometric and sensitive fluorescence response with a low detection limit (100 nM). Moreover, the probe shows high selectivity for bacterial endotoxin over other related biological species.
N,N-二甲基-N-(芘基-1-甲基)十二烷-1-铵已被设计并应用为用于检测细菌内毒素的荧光探针。在水溶液中与细菌内毒素（脂多糖）组装后，探针表现出比率和灵敏的荧光响应，检测限低（100 nM）。此外，该探针对细菌内毒素具有高于其他相关生物种类的高选择性。
