广泛耐药结核病，巴基斯坦。
Extensively drug-resistant tuberculosis, Pakistan.
机构信息
Department of Pathology and Microbiology, Aga Khan University, Karachi, Pakistan.
出版信息
Emerg Infect Dis. 2010 Sep;16(9):1473-5. doi: 10.3201/eid1609.100280.
Abstract
Frequency of extensively drug-resistant tuberculosis in Pakistan increased from 1.5% in 2006 to 4.5% in 2009 (p<0.01). To understand the epidemiology, we genotyped selected strains by using spoligotyping, mycobacterial interspersed repetitive units-variable number of tandem repeats, and IS6110 restriction fragment length polymorphism analysis.
摘要
巴基斯坦广泛耐药结核病的发病率从 2006 年的 1.5%上升至 2009 年的 4.5%（p<0.01）。为了了解其流行病学特征，我们采用 spoligotyping、分枝杆菌间隔重复单元-可变数串联重复和 IS6110 限制片段长度多态性分析对选定的菌株进行了基因分型。
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